I'm taking methotrexate to treat my Eczema (Yes i know i'm in the wrong forum) and I can see that this is not very common. I know a fair few RA patients have undergone treatment with MTX but I need some information on the alcohol consumption side of things. I took a 10mg tablet of MTX last Saturday and that was my first dosage, the next one is this Saturday. The catch is I was wondering how long the medication takes to inhibit your body due to me having a birthday/party this Friday night and I was planning to consume more than atleast three units of alcohol... Will the MTX have a big effect on my body that it's relevant to how much alcohol I consume or not? If there's a chance then i'll have to give it a miss but I need to advice and thank you all in advance!