NRAS
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Going to start Methotrexate

Hi all you lovlies.

Just got back from Rheumatologist and he said my xrays showed erosions and my ESR was still high. So along with Hydroxychloroquine I am going onto Methotrexate.

Could you share with me your initial experience on this? Sort of dreading taking it in one way but hoping I get some relief in another!

Thank you xx

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Mxt is usually the first drug given, anyway, my experience is good, best taken at night, so you sleep thru effects, if any. In the beginning, 3 yrs ago, I did feel grotty the next day, but not any more. Good luck, hope it helps you

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Thank you lab-lover. x

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Im on sulfa and having metho added in when my liver stabilises so im with u on this journey xxx

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Nice to have you along! xx

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Hi Hev, the mtx does affect us all differently. I started on it last august and the nausea was a little grotty for the first few months but an increase in folic acid helped with that. I still occasionally get a bit nauseas but I think I've just gotten used to it. All in all it's not been too bad for me.

Unfortunately it isn't helping me yet, but I tolerate it well and will probably need something added in to get things under control.

It does sound a scary old drug, but try not to worry, from what I've heard it really is a very good drug, if not the best drug for treating RA. Good luck and let us know how you get on. Rx

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Thank you Rosie, much appreciated although sorry to hear you have had nausea and still have some. Fingers crossed for you it works soon. Thanks again appreciated xx

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Hi Hev, Ive been on MTX since diagnosis 12 months ago,( I also am on Sulfa & Hydroxy) I felt really yukky the first 3-4 weeks of taking it, spoke to Rheumy nurse who said to up my folic acid which I did & asking for advice from the lovely people on here I take it at night on a sunday & sleep through any side effects. Make sure you have plenty of water/ fluids through the day, I find that helps, if I don't I get terrible headaches. All the best, Rie x

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Really useful thank you. I am picking it up tomorrow and going to start it Friday night so I can sleep and give it the weekend before work Monday. Thanks again xx

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Oh good news! I hope you get the benefit, immediately!

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scary isn't it ? I sat and looked at mine and went away about 20 times before I plucked up courage to take them , you hear all the horror stories , a little mild nausea and indigestion but omeprazole helps , they make me feel wiped out for a couple of days but it's nothing to worry about honestly. still waiting for some response , just increased the dose , hope you will be lucky and they give you relief and that you are lucky like me and don't get the side effects, x

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hi Julie just wondering what horror stories have you heard as I have been on M 7years and very ill with a HUGE stomach that cant tolerate food, had so many tests ultra sound, CT scan, berrimeal, camera up and down and still cant fix my stomach, have you heard of anyone else with thes symptoms.cheers

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nothing specific , just the usual tales of vomiting and liver problems !! I feel very bloated sometimes but nothing like you . hope you get some answers soon , this disease is horrible !!

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I could take methotrexate at all but that's just me!! I know a girl who's on 20mg and since all of her symptoms have gone. In my opinion, anyone who can take methotrexate are very lucky as it seems people on it have a very good outcome. Good luck

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I have been on 15 rising to 25 mg for 2 years and get nausea and bad mouth ulcers. Folic acid acid helps but I would like to take it every day as that really helps. I have to not take on the day and the next day now, boohoo! Anne

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Well I have my tablets and Folic Acid. Wish me luck and thank you for all you support and help xx

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Good luck and let us know how you get on

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