I am fairly new to this (very helpful and friendly) site and having read quite a few posts find that MTX is probably the first line of defence. I was immediatley put on to this plus one other as the nurse said a combination works better. I was given 15mg a week, 6 tablets, which resulted in headaches and a fuzzy feeling, so on my own decision, I decided to take 10mg, 4 tablets, and this suited me better. I rang the nurse and told her what I had done, and she said that if it suited me better, then that was ok. It still kept the pain away, so sometimes I think we have to read our own bodies, obviously the headaches were telling me it was too much.
Will there come a time when MTX may not suit me and I may have to try other medication, is this how it seems to go with most people?