Hi everyone I have not been contributing recently but have found a lot of the chat very interesting. I have been on Cimzia & MTX tablets (20mg) for the past 3years but because of the GI side effects was changed to MTX injection (20mg) 8 weeks ago. Prior to this I had difficulty eating well & had lost quite a bit of weight & was getting weaker. Initially this seemed to help with nausea but I found this dose far too strong & it greatly increased the other side effects (dry eyes & skin, mouth ulcers & pulsating headaches). Reducing the dose to 15mg has helped with these but I would say that my tummy is worse. I now can have quite a sore tummy with bouts of vomiting & the diarrhoea more frequent.