I wonder how many of us have difficulties with irritability. I hear sarcastic and snarky quips coming out of my mouth when I least expect it, but particularly when I'm tired. I spend a lot of time apologizing. I've always been very able to make stupid, thoughtless remarks long before MS, but since MS, I'm appalled at myself. I feel as though I need to apologize before I ever say anything to anybody, just in case. It makes me want to withdraw from people. Do any of you suffer with this?