Just a note really, to say hello everybody...and fellow sufferers! I'm 65, retired 3 years ago & was diagnosed with PPP, in 2004; my GP thought he had seen signs of it in 2000 - the diagnosis explained a lot & was a bit of a relief in some ways. I've been on 1 grm of Hydroxycarbamide X 5 days & 1.5 grms X 2 days...and have been suffering from a poor sleep pattern (worse than normal poor sleep pattern) since the increase - about 12 months now. A steady increase in dosage since 2006 now! Really fed up & thinking I need to see the GP again to try & get it sorted, maybe CBT? Does anybody have any thoughts/remedies for this poor sleep pattern. I do manage to live a relatively normal life with the help of my wife, to whom I owe a great debt; she is, without a doubt my best buddy & nurse all rolled into one! Life would be OK if, I could manage this sleep problem so, again - any thoughts?