I have had ET now for 16 years and been on oral chemo for 10 years. Recently been feeling weak with chills and sweats. My bones and joints start to ache around 5 pm every day! It is weird. I feel that I have a constant virus and cannot shake it off. My white count is 3 at the moment. My RBC is 11. I look so pale. I am afraid that my condition is worsening. Not had a bone marrow biopsy for 5 years now so may think I need another one. Any comments please..