I did the CBC at mt hematology office today as planned. Recall this from my last post..
My most recent CBC at the PCP 09/06/24 shows HCT=46.2 HGB=14.7. The CBC at my local hematologist on 08/02/24 showed HCT=42.7 HGB=14.2. It seems a rather large jump in a short period of time given that the HCT has been stable in recent months. I am thinking this may be an anomaly, which has happened in the past. I am scheduled for a CBC at my local hematologist on 09/27/24. I am planning planning to defer doing anything until the HCT/HGB numbers are confirmed. If confirmed, will schedule a phlebotomy.
As of today 09/27/24 HCT=44.2 HGB=14.5. As I expected, I do not need to consider a phlebotomy at this point in time. The higher read at 46.2 appears to have been an anomaly. Perhaps the time of day for the higher read, 8:30am, and the fact that is was a fasting blood test, possible lower hydration, played a role. We will likely never know for sure, but it is all good.
My next CBC will be 12/02/24. We are planning a repeat of the JAK2 quantitative analysis at that time.
Until the next time, wishing all of you all the best.
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hunter5582
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Thank you for sharing hunter5582 , good to know you didn't need the phlebotomy.
In a previous post, I'd noticed you'd commented on levels for bloods taken at a different time of day can differ, and I have also seen this in my own results too. I agree hydration may well play a significant part as, blood taken early morning had higher levels than other test taken late afternoon. Following your comments/ observations,I now stick to late afternoon blood tests.
I hope all goes well for you and I shall look forward to hearing your JAK 2 news.
Thank you for helping us all to understand our MPNs and your ongoing support xx
I had a similar experience recently Hunter. In a 2 day period my Hct went from 45.9 (Sep 16) to 41.3 ( Sep 18). Blood was taken at the same time of day and post lunch I.e. 2.00pm
Two factors I believed contributed to the difference. On the 16th I had a pretty strenuous 1 hour work out in the early morning with heart rate near max for 20 plus minutes. I think this level of aerobic exercise could resulted in splenic release of stored RBCs as happens with exercise which would drive up HCT in contrast on the 18th I had a very relaxed day with no exercise at all
Second factor was difference in hydration levels - using the total protein levels measured on the 16 and 18 vs Hct indicated that 1.5% could be explained by hydration.
Lesson learned going forward is no strenuous exercise on the day of a blood sampling or scheduled phlebotomy and drink plenty of water!
Good news. Well done. I am sure a blood test early in the day will affect blood results if test normally carried out later in day. Always try to get mine done around midday having drunk gallons of water😅
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