Polychromasia in peripheral smear?

[Xuzy]

I'm 23 M Jak2 negative, bmb inconclusive, done in 2018

Recent peripheral smear shows anisocytosis and polychromasia. Is this worrisome feature? Am i landing up in something serious?

[hunter5582]

Anisocytosis = red blood cells that are of different sizes.

Polychromasia = more immature red blood cells than what's considered normal

Polychromasia (variation in colour of stained RBCs) and anisocytosis (variation in size of RBCs) are features of a regenerative anaemia. Polychromasia is due to early release of young cells from the bone marrow. vin.com/apputil/content/def....

In the context of a MPN there could be different reasons for this finding, including treatments you may be undergoing. This may not be a big deal, but neither is it something to ignore. Suggest that you take this finding back to your MPN Specialist for an answer.

Please do let us know what you learn and how you get on.