question of the day!: does asprin actually lower... - MPN Voice

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question of the day!

Carthe profile image
Carthe
•4 Replies

does asprin actually lower platelets or just stop them sticking? Thank you 😀

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Carthe
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ainslie profile image
ainslie

reduces stickiness, doesn’t lower

Mirror368 profile image
Mirror368 in reply to ainslie

Aspirin helps prevents blood clots, does not lower platelets.. I was already on a blood thinner for AfFib so do not need to take low dose aspirin.

Wyebird profile image
Wyebird

I believe it stops them sticking hence other meds required in some cases

PhysAssist profile image
PhysAssist

Hi Carthe,

I found this while looking for information about PRP therapy for another post.

"A Systematic Review on the Effect of Common Medications on Platelet Count and Function: Which Medications Should Be Stopped Before Getting a Platelet-Rich Plasma Injection?" from here: ncbi.nlm.nih.gov/pmc/articl...

It's overall too much information for this questions, but it does answer it:

"Aspirin Patients who were randomized to differing doses of aspirin were consistently shown to exhibit decreased platelet aggregation when compared with patients randomized to placebo. 3,6,13 –15,22,32 A cohort study by Wientong et al 43 similarly found that aspirin therapy led to a decrease in platelet aggregation compared with control patients. This study showed that patients taking 60-mg/d aspirin had a mean platelet aggregation of 18% compared with 79% in control patients...."

O n the other hand:

"Three studies found that aspirin treatment did not lead to a significant change in platelet count. 6,15,16 Interestingly, Erhart et al 10 found that healthy patients treated with 250-mg/d aspirin for 7 days displayed an increased platelet count."

I hope this helps.

Best,

PA

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