Hi everyoneI've been taking Anagrelide for 6 weeks now and I'm putting on a lot of weight suddenly, especially in my face. Plus a thumping heart sometimes. Does anyone know if these side effects lessen with time?
Anagrelide side effects: Hi everyoneI've been... - MPN Voice
Anagrelide side effects
![Sivasi profile image](https://images.hu-production.be/avatars/6b479f870e0343568a5679c972822f74_small@2x_100x100.jpg)
![Sivasi profile image](https://images.hu-production.be/avatars/6b479f870e0343568a5679c972822f74_small@2x_100x100.jpg)
Both symptoms you listed are known side effects from anagrelide. This source notes these adverse effects as something to notify your doctor about immediately.
mayoclinic.org/drugs-supple...
Suggest you review your adverse effects with your care team ASAP.
hunter, I was doing inflammation research and came across this article. Are you familiar with
PPARγ agonists?
I’ve been on Anagrelide for a few years, I got quite a lot of palpitations at first but they gradually faded. If I get them now it’s around 2 hours after I take the capsules. Platelets now in normal levels, however keep an eye on other counts, I’m very anaemic and am now pre-mf possibly partially caused by the Anagrelide. Wishing you all the best.
I’ve been on ana for almost two years and had scary heart palpitations for a few weeks. Completely gone now! Didn’t experience weight gain though but that might also fade as your body gets used to it… Hope it works out. Ps I will switch to Peg in about 6 months because of the better long-term prospects
Yes the side effects do die down....I had terrible heart palpitations at first....now I don't have them. Still get ET side effects, tiredness, headaches etc
Keep going with the meds to give it a chance