This one is good results, I've been sharing some info from it. I hope they provide the full text eventually. This plot sums it up well. Ropeg had less progression esp after many years.
"20 years after diagnosis, 85% of PV patients who had been treated with interferon had not progressed to MF compared to 59% for the HU group and 51% of the phebotomy-only group."
"overall survival for patients on interferon was 95% compared to 63% for HU and 57% for phlebotomy-only."
It was actually for the older non-peg formulation from the description. That seems reasonable since pegintron or pegasys were not available in the early part of these studies. Could be the later portions of the study were with peg.
I've not seen this specific one, thanks. It's consistent on thrombotic events, I recall most studies don't find a big diff between HU and INF. But for allele (AB) it is too short duration, INF needs longer periods (than 24 months) to show its best effects.
But it is consistent at 2 years (Fig 3) showing HU losing its AB effect while INF is just getting started, we see this in almost all such studies.
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