-Both of Hypertension and Fatigue, HU: 3%, PEG: 7%
-Headache, HU: 0%. PEG: 4%.
Some increased fatigue on INF is common on the forum, I have had some myself. We have seen members with headache on INF. Hypertension is the biggest surprise here for me. I've actually had more consistent BP since starting INF, this allowed me to increase my still low dose BP med. Any others with BP changes on INF?
There is a separate finding <<HU produced a greater histopathologic response>> It was a big difference. I think this is for marrow condition, but it can also refer to blood condition. HU is not known to improve marrow from what I've read. They don't define it further.
Thanks for that interesting post. Blood pressure slightly higher on peg but not too bad. I check it once a week. Before peg it would go to a good range if I behaved myself but seems stuck at 130/85 on average at the mo
No change in BP that I have seen on PEG or Besremi. My BP did improve when the erythrocytosis was under better control from the phlebotomies. The improvement has been maintained on the IFNs. Definitely better to not have the blood too thick.
Thank you, those snippets of information are Bril bite size and easily digested.For me being on Peg, fatigue is far far less of an issue. I think it depends on how anaemic on hu you are etc.
I don’t ever want to be put back on hu and anagrelide again. For me Peg I know not for others gave me a reason to live life again.
Interesting on the BP - I did not know that was even a possible AE. I have always had higher than normal BP but amazing cholesterol and am active and do extremely well on heart function tests so my doctor has always said that perhaps I am just a little "north of normal"..but in my last reading at the doctor's office the BP was highest it had ever been at 145/85. My doctor asked if it could be a side effect of the Peg and I said I was not aware of that but will ask my MPN specialist when I see him next week (liver readings def a Peg AE and we are assuming a few wonky Thyroid readings as well). So I will ask and report back...actually the BP reading gave me the impetus to finally lose those last 5 kgs/11 lbs and reduce my salt intake as much as possible!
Just came in from a walk, having done my 26th PEG injection - no issues, thankfully. Took two BP readings after relaxing for 5mins: 1st: 114/76; 2nd: 104/70. I added 2.5mg Amlodipine to my 5mg Ramipril, as the increase in Ramipril was pushing the potassium up. No AEs from any of the meds. Aiming to lose half a stone, though, as have been eating too many treats lately…!
I have a sweet tooth - going cold turkey for a while.Re. Prof Harrison: no, not yet. My haem sent me a copy of the letter she wrote to her, asking for her expert opinion. It may well be that she only writes back, rather than requests an appointment with me. Either way, I suspect she’ll want me to have a BMB.
From all my GP appointments, I gather it’s the trend that matters with BP, not the occasional aberration. As you know, they’re well used to ‘white coat syndrome’ too. Home readings are the best!
Great replies. It seems no big issues for members with Lymphopenia. I know some of us are low but still ok.
On BP I actually forgot an episode I had early in my Bes treatments. I started a few at 50mcg per HU transition, no problems. Then 110mcg. The next week BP was ~165/~100. (similar to my pre-treatment BP at Dx.) It went down quickly after that. My Dr was ok with it, saying it's the INF, so I am a data point on the AEs above.
So my case does support a short hypertension episode. I was thinking of durable problems, so forgot this one.
I knew about this short episode only bec I regularly use a home BP device. If you get too high BPs at Dr's office, as I do, I suggest you get one to know your real daily levels. I'm listed as HTN (hi BP) on my patient records because that is what they see at the office, so I reassure my self and Drs with these measurements.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Peg Interferon Journey
3 Peg injections later
