Covid Vaccination- Thanks for all replies

[azaelea]

I'd like to thank you all very much for your very helpful views on this matter. My hospital, James Cook in Middlesbrough has begun vaccinating today. I 'd just like to know (what nobody does know yet) what side effects it could have on the body. I'm suffering a few at present from Hydroxy side effects and wouldn't want to add to them. Will wait and see. Your replies have been so helpful. We're so lucky to have this Group to talk things over with fellow MPNers. Regards, Fran

[Wyebird]

Hi, my heamo is an MPN specialist. I think the general rule is it’s ok and that needs will be balanced with risks. We are all so different.

[Ovingite]

Hi Azaelea,The way I look at it is that there appears to be a small risk of quite minor side effects from the vaccination, which needs to be balanced against the fact that Covid-19 has already taken the lives of one in every thousand people on this island (and it isn't done yet!). It has also severely debilitated many others and left them with a poorer quality of life.

Of course it is up to every individual to make their own decisions, but for me it's a no-brainer and the sooner I can get vaccinated and return to a near normal life the better.

I wish you well whichever path you choose

John

[lizzziep]

I hope you can get the vaccination and it doesn't leave any side effects. We're all apprehensive about it, but the vaccination seems to be a better option than Covid! XX

[rebeccaxxx]

I always find reading the green book helpful when deciding on vaccinations gov.uk/government/publicati...

[rebeccaxxx]

Here is the section on side effects:Adverse events

Local reactions at the injection site are fairly common after Pfizer BioNTech COVID-19 vaccine, primarily pain at the injection site, usually without redness and swelling. Systemic events reported were generally mild and short lived (Walsh et al, 2020). In the final safety analysis of over 21,000 participants 16 years and older, the most common events were injection site pain (>80%), fatigue (>60%), and headache (>50%). Myalgia, arthralgia and chills were also common with fever in 10-20%. Most were classified as mild or moderate. Lymphadenopathy was reported in less than 1%.

In an earlier analysis of around 8,000 recipient, severe side effects, defined as those that interfere with daily activity, included fatigue in around 4% and headache in 2%. Older adults tend to report fewer adverse events following vaccination. This earlier analysis also showed no signal for enhanced disease in vaccine recipients with only 1 case of severe COVID in the 8 vaccine failures at that time.

businesswire.com/news/home/...

Chapter 14a - 14

COVID-19 - SARS-Cov-2

Chapter 14a - COVID-19 - SARS-CoV-2 December 2020 Provisional guidance subject to MHRA approval of vaccine supply

From early phase trials, mild pain and tenderness at the injection site was common with AstraZeneca COVID- 19 vaccine occurring in 88% of 18-55 year olds, 73% of 56-69 year olds and 61% of people aged 70 years or over; similar levels were reported after each dose. Short lived systemic symptoms including fatigue and headache were also common but decreased with age, being reported in 86%, 77%, and 65% of those aged 18-55, 56-69 and 70 years or over respectively; most of these were classified as mild or moderate. These reactions were unusual after the second dose (Ramasamy et al, 2020). Mild fever (>38 ̊C) was recorded in the first 48 hours for around a quarter of younger participants and but was not reported in those over 55 years of age or in any age group after the second dose (Ramasamy et al, 2020). Fever can be modified by the prophylactic use of paracetamol, which does not affect the immune response to this vaccine (Folegatti et al, 2020).

Vaccinated individuals should be advised that the COVID-19 vaccine may cause a mild fever which usually resolves within 48 hours. This is a common, expected reaction and isolation is not required unless COVID-19 is suspected.

[azaelea in reply to rebeccaxxx]

Thank you so much Rebecca for your very helpful post. I wasn't aware of The Green Book. I'm sure this will help a lot of us. Regards, Fran

[MPort]

Thank you for posting the evidence from the report. I watch Dr John Campbell on YouTube. He does the same. Yesterday he looked at evidence in the Oxford vaccine papers that were available for peer review. He explained the results. They are very reassuring. It gives me hope. Keep well.