LDH lactate dehydrogenase test ranges .
Is it required to get this test done from time to time as it gives idea of tissue damage and disease progression ?
Diff labs in diff countries diff ranges i believe i got 250 and the lab range was 230- 480 U/L
I googled it says normal range is 140- 250 for adults ? And at times its measured in iu/L also so can any one affirm the ranges criterea differs with diff labs idk why my lab had a normal range of 230-480 ?
Thank you very much,a helpful piece of information.Good that there are markers to inform us of how the body is coping!
Hi it looks like I was tested for this in 2018 on my result of 317 the range was 125-243 at Hammersmith hospital
Hello, Aojai, I was diagnosed with ET Jak 2 in 2008 but I never heard of LDH until last year when I switched hematologists. I’m in the US and the normal range is up to 250. My LDH was in the 700’s. After being treated by her for the last nine months, it is now almost in the normal range. She also diagnosed me at that time with post ETMF and anemia. I’m feeling a lot better now since most of my numbers are in the normal range. She really only worries about my hemoglobin and my platelet count, but I was shocked to see my LDH was so high at the time. I wish you all the best.
What were u treated with i believe post et mf must hav been diagnosed after a new bmb , from replies by fellow members i think diff labs have diff ranges and cut off point for ldh ....
Yeah so I changed hematologists after 11 years because about a year and a half ago I started feeling really awful. I could barely concentrate on my work and by 3 PM I could barely even hold up my head or keep my eyes open. My hematologist couldn’t figure it out and I decided to go find an MPN specialist. She was the one that tested me for my LDH levels. And yes, I did have a second BMB, as well as an ultrasound, And more bloodwork than my original hematologist had ever done. My LDH was 648. This was last September. My most recent LDH levels were 313 on May 22. My hemoglobin, which was 8.9 when I started with her is now 11.4. I’m feeling better than I have in years.
I take Hydrea every day but she added a new drug called fedratinib, Which is specifically for somebody with MF. I also take baby aspirin.
Hi Aojai, I'm glad you asked this question. I was diagnosed with PV 4 years ago now and take hydroxy which controls things well and I have few symptoms. However at my last appointment my haem decided to have LDH tested (never had this before). The result was 495 IU/L (with a normal range of 164-412). I am not clear what this test is indicating, other than in the broadest terms, tissue damage. I have googled it, but am not much wiser as far as my MPN is concerned. If anyone can throw any light on this, I would be very interested.
Hi! I dont get this one. Do you know more about it now? My levels were a little bit high. What does tissue damage really mean? Is that normal in ET?
I have read that the LDH level can be used as a fairly reliable indicator of disease progression . I have an appointment with my haem in London soon and will ask more then. My levels have varied up and down by 50 IU/L in the last 6 months. No trend.
Puzzling Labs last 4 years
JAK2 Allele Burden On Pegasys
Besremi working well- 150 mcg every month instead of bi-weekly 
PVR blood test results
Update 7.0
