Any news,trials or progress on use of CAR T-cell therapy for Myelofibrosis or related conditions?

[Innessant]

A true breakthrough in several diseases , especially cancers eg Leukemia. Costly ( $1m per treatment) but costs will decline . This is the use of your own (tweaked) immune suppression systems to fight cancers.( see TED Talks etc).

[Paul123456]

My very limited understanding is that this is some way off re MPNs because most of us have dual genes eg JAK2 % Allele Burden of mutant gene.

However I’d like some to explain to me why/whether those who are triple negative might not be possible short term targets.