Latest paper from Prof Harrison

[Paul123456]

Interesting new research, early days. Not that significant re reducing Allele Burden but initial results appear promising re reducing reticulin fibrosis. Established drug with good tolerance profile.

haematologica.org/content/1...

[Meatloaf9]

Thanks for posting. In lay person language what does this mean for the MPN population of patients?

[Kelly2 in reply to Meatloaf9]

😀

[Paul123456 in reply to Meatloaf9]

I’m not sure. Collagen fibrosity is of greater concern than Reticulin re MF. Will this work on Collagen? Whatever, it’s early days but appears a step in the right direction.

There is now a lot of research into MPNs after years of falling below the radar. Has to be highly encouraging re new treatment options within next few years. Evidently arsenic combined with Interferon has produced some great results, albeit in mice! Human trials next step.

[Meatloaf9 in reply to Paul123456]

Thanks Paul

[Lab-Rat]

Another publication on Mirabegron and MPNs:

haematologica.org/content/1...