New combo drug (Ruxo) for MF: Umbralisib Still in... - MPN Voice

MPN Voice

10,762 members14,928 posts

New combo drug (Ruxo) for MF

Paul123456 profile image
9 Replies

Umbralisib

Still in trials but promising results so far.

hematologytimes.com/section...

Written by
Paul123456 profile image
Paul123456
To view profiles and participate in discussions please or .
9 Replies
Rachelthepotter profile image
Rachelthepotter

Thanks for this, Paul.

Paul123456 profile image
Paul123456

And the ongoing trials

clinicaltrials.gov/ct2/show...

mammared profile image
mammared

The more we learn, the better we become. Thank you for posting this very promising news.

Paul123456 profile image
Paul123456

I’ve been chatting to the patient (Patient 2 in the article above) in complete remission.

“Yes. That’s me. They call me post-PV MF because my 1st doc did phlebotomies when my HCT got especially high in 2012 but I was diagnosed with primary MF in 2007. My bone marrow has always been atypical so the team now thinks I may have had undetected PV. ??? But 2 labs in 2007 said atypical primary MF. Who knows? Anyway, I’m now in cycle 14 and still doing great. Here’s another article: “

tgtherapeutics.com/Final%20...

She is JAK2 + and TET2. Patient 1 the same and he has done well post SCT

mammared profile image
mammared

Yea! This is terrific news! Thanks for sharing. So very happy for you.

B

Wyebird profile image
Wyebird

What would I do without you.

Many thanks. Fab news for MF sufferers.

beetle profile image
beetle

Thank you for bringing this to our attention. You are so good at keeping us all informed and I for one really appreciate it

Paul123456 profile image
Paul123456

This is another useful combo trial, Pegasys plus Ruxo. Looks worth checking out for early stage MF.

onlinelibrary.wiley.com/doi...

Bluetop profile image
Bluetop

Thanks Paul for all this promising information.

Not what you're looking for?

You may also like...

Ruxo for mf cost? Nhs?

I have just been diagnosed with mf and have heard about ruxo. Is it helpful from the start? What...

Potential New MF Drug

CPI-0610 Demonstrates Activity in Patients With Myelofibrosis After Ruxolitinib Failure Post...

New Drug may be relevant to MF, ET

A new drug for pulmonary hypertension, (PAH) Sotatercept, has just been approved. PAH is not a...

New to MF

Hi I have et and recently been told It has progressed to MF. I'm to see my consultant on Monday to...

Myelophibrosis and Ruxo

Hi! My mom has MF for 8 years and all of them is on Ruxo, but lately she started to feel...