Does anyone else struggle with inflammation? I am 51 years old, and was diagnosed with PV two years ago. I began taking Peg-Interferon 3 months ago, and at about that same time, began noticing inflammation. My fingers are swollen to the point that it is difficult to wear my wedding ring. I have not gained any weight, am drinking plenty of water, and eat a healthy diet. Wondering if anyone else has experienced this, or if you think it could be related to PV and/or Pegasys. Thanks!