I have ET (MPL) I also have MTHFA which I gather is unrelated to ET, I wonder if it is unrelated, has anyone else got MTHFA mutation. MTHFA is the process of methylation also involves the enzyme from the MTHFR gene, so those with a mutation may have trouble effectively eliminating toxins from the body. The genetics home reference offers more detail: The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase.
MTHFA Gene Mutation : I have ET (MPL) I also have... - MPN Voice
MTHFA Gene Mutation
Written by
Raphael_UK
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2 Replies
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Hi. I have CLL as well as JAK2 +ve
myelofibrosis. Dont know what the mutation is thst caused the Cll
Rachel
I haven’t been tested but my brother has a MTHFR mutation. My understanding is that half the population has it so I’m not sure whether it has much significance in MPNs.
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