Topiramate - best time to take it

[Brychni]

Hello again

So I upped the dose to 75mg, taking 25mg in the morning and 50mg in the evening but this only lasted 3 days as I was hardly ale to function. For three days I have dropped back down to 50mg taking 25mg am/pm. However, I have noticed that the drowsy effects seem to creep up after about an hour of taking the tablet and wonder if there is any reason not to take both in the evening? Do I have to spread the dose? I was happy taking 50mg and remained headache free and felt no 'shadows' lurking and was clear headed so didn't really want to up the dose, it was just what the neurologist advised. Is there any reason not to just take both tablets at bed time?

Thanks

[Lacycat1234]

Have you explained this to your doctor? They do medication adjustments. He would be the best one to answer your question.

[Dazakella2010]

I take 100mg and I take this at night before bed.

[troy04]

Is there a reason why the doctor increased the dose? If previous schedule was working, not sure what's the point of experiments. It is hard enough to find right medicine and dose that works.

[Penys]

I take 300mg a day, 150mg in the morning and 150mg in the evening that is by orders of my neurologist. It did take roughly 2 weeks for my body to adjust every time my dose was increased and then it would settle and all be fine.Everyone's different though.

I wouldn't change anything without talking to my neurologist.

[Johnny-One]

I was always told with Topiramate you take more in the eveing for headaches or more in the morning for Epilepsy. So if you are taking 3 tablets 25mg each for headaches you would take the 25mg x 1 AM and 25mg x 2 PM; but for Epilepsy it would be the other way around.

That is what I was advised by my neurologist when I first started taking them.

I am on 250mg so I take 100mg AM and 150mg PM.

[LkJ03]

Hi i took 50mg in morning and 50mg in evening but felt as you did so took 100mg in evening and this was much better

[chicolini]

PS l started the aspirin after discussion with my GP who was interested and supportive of the idea. Also l forgot to mention it was a hospital specialist who first mentioned cortical spreading depression to me as a cause of aura. The articles l found were all scholarly reports in medical journals by doctors and researchers.