I have suffered with migraines for over 60 years. Most recently I was getting an average of 15 migraines with aura a month. I also have antiphospholipid syndrome. In the summer of 2017 my neurologist initially put me on topamax twice a day working me up to 100 mg a day. I hated the side effects of feeling groggy, nauseus and having word retrieval issues. In the late fall of 2017 the FDA in the States approved the use of the time release version of Topamax for migraines to be covered by insurance. It is marketed as Trokendi XR. It has been a life saver. I experience no side effects and very rarely have a migraine. Ask your doctor about the time release version taken once daily. I hope it gives you relief!