Statins 'could treat prostate cancer': Cholesterol-busting drugs starve stubborn tumours, first of its kind trial finds

[George71]

11 out of 12 prostate cancer patients saw their tumour growth slow after statins

This indicated they were seeing 'disease stabilisation', the researchers say

Drugs could be offered to patients 'very quickly' if further studies show effect

Patients were given a 40mg atorvastatin pill every day for six weeks.

dailymail.co.uk/health/arti...

[Scout4answers]

my research says pitavastatin works even better.

[Lyubov]

Curious: do statins have give similar help in other cancers besides prostate?

[NPfisherman]

I guess my question is how do statins stack up against bempedoic acid ?? Both reduce cholesterol, but by different ways... The good news....all are approved and negatively impact PCa......

Thanks George71

Fish

[cesces]

Dr. Myers was doing that for yeats.

For some pathway reason he preferred rouvastatin.

[Seasid in reply to cesces]

Rosuvastatin (crestor) i was taking 40 mg per day without any problem. I stopped and I am now on drug holiday.

[GreenStreet]

George thanks for posting 👍

[Rolphs]

This would be great news if these results are validated by RCTs. I was just put on atorvastatin for high cholesterol and I might be getting a an added benefit of slowing PCa. Thanks !

[cujoe]

Thanks for the post, George. I've gotten amazing results from using Cholestene, a red yeast rice supplement that has tested (Consumer Labs) to be equal to lovastatin. I guess my question is the proverbial one of: Is the benefit related to the improved cholesterol/lipid profile or some other action of the various pharma statins?

There is also much evidence (correlation vs causation?) that low HDL is seen in various cancers. I started the Cholestene due to below normal HDL and saw it nearly double from 37 to 62 after just 3 mos on the supplement. I am now trying to decide if raising HDL was a good or bad thing for my 2 x cancers - since there is evidence that both can use HDL for fuel = could low HDL in my case be a "good thing"? (I've cut my daily dosage in half and will test lipids again in December.)

Unravelling the mysteries of cancer(s) is a near full-time job. Ciao - K9

[lokibear0803]

FWIW, I use a media fact check website for sources I’m not familiar with. Here’s their take on Daily Mail (hint: not flattering):

mediabiasfactcheck.com/dail...

Of course, there is the question of just who is Media Bias Fact Check; for starters, they are pretty transparent about their methodology. But still…

Undaunted I asked Media Bias Fact Check what their opinion was of Media Bias Fact Check. The rating was pretty high 😎

[George71]

"The trial was conducted at the Beatson West of Scotland Cancer Centre." and reported out by the BJU International (British Journal of Urology International)

bjui-journals.onlinelibrary...

[Benkaymel in reply to George71]

The Results discussion states;

" ... the majority (n = 11) of the 12 evaluable cases recorded a decrease in PSA levels"

but that is just saying that there was at least one pair of consecutive PSA readings where it dropped. Table 1 of results shows that all bar 2 of the 12 participants had an overall increase in PSA over the 6 weeks.

I've been on 20mg Atorvastin (for high cholesterol) for around 5 years and it obviously didn't stop me getting PCa. Maybe 40mg would have done better but these results don't seem to support that.

[George71]

I agree, it isn't going to cure or prevent PCa but it appears to help slow it down which is what we are all trying to do. Slow it down and out live it.