FDA grants accelerated approval to rucaparib for BRCA-mutated metastatic castration-resistant prostate cancer

[cujoe]

From several day ago. A new treatment tool for mCRPC patients with BRCA mutations. From the FDA:

fda.gov/drugs/fda-grants-ac...

And to help understand the basics of PARP inhibitors in BRCA mutated PCa, here is an brief overview from CancerConnect:

news.cancerconnect.com/pros...

Stay Safe & Be Well - Captain K9

[cujoe]

Your inputs are always additive. We all benefit from them. Enjoy the clean, clear mountain air in your summer home & Stay Well - Cujoe

[cujoe]

Glad to hear that you are able to take advantage of the new "tools". Maybe one day soon the coming science will deliver the illusive PCa silver bullet. Give Patrick our best when you next see him. When it comes to our patient knowledge-base, you two are a real-life dynamic duo. Best regards, Captain K9

[cujoe]

950 mg (two caps) first thing in AM (empty stomach) w/ 15-20 mins before anti-inflammatory supplements batch and then 20-30 mins before eating.

950 mg near bedtime and 20-30 mins before Natto-Serra and 10-15 mg melatonin @ bedtime.

Other supplements in between. I'm due for about 2 1/2 weeks and will report any significant changes - since I added the NLE several weeks before my last labs in December.

The dosage was based on the CLL patient at Mayo FLA (+/- 1000mg twice a day). I'm taking it independent of other supplements to try to isolate any short-term effects with the upcoming lab results. Timing, etc., is just pure speculation. As you already know, my initial interest in NLE was for my CLL. Since I have never needed treatment for that cancer, I am hoping to be able to keep it that way. When I did follow-up research on it, I found equal amounts of compelling research for it's effectiveness on PCa. I'll report my lab results here or in a direct message when I get them.

Captain K9

PS When do you go off your vacation? And what indicators do you use to make that decision? Just Wondering.