Heat Exposure Linked to Faster Kidney Function Decline in CKD Patients: Key Insights from DAPA-CKD Trial

[AnnaHU]

A recent analysis of the DAPA-CKD trial has revealed that hot weather can speed up the decline in kidney function for people with chronic kidney disease (CKD). Here are the main points you need to know:

• Study Scope: The study looked at data from the DAPA-CKD trial, which included 4,017 CKD patients from 373 centers around the world. The trial ran from February 2017 to June 2020.

• Key Finding: Patients living in hotter areas had a quicker drop in their kidney function compared to those in cooler areas. Patients at the hottest 5% of centers experienced more than 60% of days with a heat index over 30°C.

• Methodology: Researchers used a model to study changes in kidney function (measured by eGFR) and looked at heat index levels from 27°C to 32°C. They also used another method to make sure the results were accurate.

• Implications: These findings suggest that CKD patients in hot climates may need to take extra care to protect their kidneys. This could include staying hydrated, avoiding outdoor activities during peak heat, and monitoring kidney function more closely during hot weather.

Understanding how heat affects chronic kidney disease is important for CKD patients and caregivers. This study highlights the need for awareness and proactive management of CKD in hot weather.

For more detailed information on this study and its findings, you can read the full research paper here: thelancet.com/journals/lanp...

Join the Discussion

- How do you manage your CKD during periods of high heat?

- Have you noticed any changes in your kidney function during different weather conditions?

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Glossary

- Estimated Glomerular Filtration Rate (eGFR): A test used to check how well the kidneys are working.

- Heat Index: A measure that combines air temperature and humidity to give an apparent temperature.

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Citation

Caplin B, Zhang Z, Mistry MN, et al. Association between heat index and change in estimated glomerular filtration rate in patients with chronic kidney disease: a post-hoc analysis of the DAPA-CKD trial. Lancet Planet Health. 2024;8:e225-e234.

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Disclaimer

This summary was AI-generated. Please consult your healthcare professional before making any changes based on this content. Be aware of potential inaccuracies in AI-generated summaries.

[MaddieHU HealthUnlocked]

Thanks for sharing this research AnnaHU . I knew high temperatures can lead to more hospital visits for kidney stones and acute kidney problems, but it's very insightful to learn how everyday heat can affect people living with CKD.

[orangecity41]

I was diagnosed at CKD level 4, and live in a sub tropical climate in central Florida, and with CKD diet it has declined. I do spend time outside in swimming pool and walking in the heat also. Just sharing my CKD history.