If we lower the levels of acetylcholine i... - Cure Parkinson's
If we lower the levels of acetylcholine in our bodies do you think it would help to regulate the dopamine levels?
im not a dr. but was a paramedic. that may be kinda dangerous, Ach is a neuro transmitter in both cns and pns. example your heart rate would be tachy because Ach slows it down.
Im seeing a kinesiologist who is giving me zinc sulphate and other advice to lower the levels of acetylcholine and then he thinks the body will be strong enough to sort out dopamine levels...i am a sceptic but if not too dangerous it might be worth trying. I havent started any meds yet...
interesting, dont be a sceptic in yourtreatment. you need to believe. old hawaiian kahunas used to ask people " do you believe i can help you" if theyd say yes, they would help them, in no then they wouldnt. the power of the mind is awesome. you just gotta believe it will work. keep us informed of how it goes. aloha
Thanks for that reminder. I'll try to keep a positive attitude with my accupuncture.
Acupuncture has really helped me •••• but like Pacdiver said, you have to believe. Your mind is a great healer!
Balancing acetylcholine with dopamine and other transmitters is very important for symptom control. this can be accomplished with anticholinergics. Too much acetylcholine is toxic. i think many pwp should try an anitcholinergic if they have weakness anywhere or dystonia upon awakening.
Acetylcholine is used in making chemical weapons and it can cause paralysis.
I AM NOT A DOCTOR - just a pwp with 20 yr, experience. ask your doctor of course.
paula
could you tell me more about the relationship between acetylcholine and dopamine? how does acetylcholine buildup in the body? How do you get rid of it? What are anticholinergics?
Im just learning myself;; I think with too much toxicity in the body-heavy metal, chemicals and mercury::: but he seems to think people with too much acetylcholine have a bit of a control problem. he has told me to say this affirmation every night just as dropping off to sleep for thirty days so it goes into the subconscious; He muscle tested and said that my subconscious wants to be ill although consciously i want to get better! if anyone wants to try it!
'I truly want to release my unconscious emotion of pride and scorn now and for ever'
That and zinc supplements;;but consult a specialist kinesiologist first. as type and amount of zinc is important.
scroll thru all of this at your leisure - it's a very good site
benbest.com/science/anatmin...
these people agree with you:
barchester.com/Media/News/2...
paula
anticholinergics block acetylcholine , reducing it so that it does not get so out of balance with dopamine. Norepinephrine is also missing in some pwp brains at autopsy.This, combined with too much gluatamate and acetylcholine, and too little Gaba - the brakes, results in malfunction that only our medications can control. Artane is one example, but there are many and have different names in different countries. Google anticholinergic drugs.
paula
Thank you,.all very interesting..one never knows whether one is doing more harm than good..it is so complicated to get a balance and we are all different, ive been put off drugs so far as side effects seem worse than putting up with my symptoms so far! My partner thinks i am mad..but none of them slow down the progress of disese so best to try a healthy life style and natural things..i prefer to take a xinc sulphate supplement to anticholinergic drugs!
Prior to levodopa some of the medications used for Parkinson were anticholinergics. They are now frowned on for older people as they were implicated in some way with foggy thinking in people with AD. This is not to say they are not used though, as there are a lot of drugs that fall into this category. Some of the most commonly used ones are to maintain bladder control for neurogenic bladder and urge incontinence. Acetylcholine in the body helps control muscle activity. Here is a very simple way of looking at it: muscles work to produce movement by pushing and pulling, dopamine and aceylcholine work together to do this, one pushing and one pulling. My urologist was aware when he prescribed me a list of several medications to help with bladder issues that they would have an effect on my PD, and was not surprised when I said they had. They help with mobility, though I ache a little more. Occasionally I have to discontinue taking them as they become less effective over time. At these times I am noticeably less mobile.
Muscles don't push. Muscles only pull.
This is a matter of semantics only, muscles contract and relax, this is how we move, the way they do that is througgh a lightning fast adjustment of neurotransmision, that in PD becomes dysfuntional through imbalance. This is why we have already lost a great deal of the relevant neurons before we really are affected, but once we are in it - PD - we also have better and worse times especially after being treated with dopamine replacement drugs. There is a lot going on these days in terms of other research that is not so dopamine focused, for sure exercise is one of the most important but not achievable by all dependent upon co-existing conditions, so other paradigms are also needed. An interesting line of research is the role of mitochondria in PD, but really there is some vey good research happening and keeping up with it is instructive.
thanks lindy, it's important to know that this illness is not just about dopamine. all the neurotransmitters need to be in balance. it's fascinating stuff to learn about, if you are interested.
paula
I'm interested but as you say it is so complex balancing everything its hard t know what to do. Takng srong medication in my view could help symtoms but make things worse by causing other problems.. why I prefer the natural route reallly. The idea of homeopathy the body healing itself appeals, along with exercise, diet and acupuncture. I wsh research woud try follwing the mre natural routes and also a whole body mind approach. It just seems geared financiallly-along with pharmaceutical companies to make better medicines for dealing with symptoms not causes..
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