Levodopa reactions

[DiyChas]

My wife is in early stage PD at 78.She is taking (and adjusting to) levodopa.

Her neurologist is quite vague on this med but indicated it is the one she should take.

She is having trouble sleeping and bowel problems.

She has leeway in drug concentrations but prefer to stay with what he says until he decides to alter.

My wife's anxiety is being affected and I am wondering, as spouse, if there are things I can do (other than asking her to relax).

Anyone else working with levodopa?

[DogsWoode]

Hi there. Just about all of us. My suggestion would be to go to all the related posts on this question....there's a whole library of questions and discussions around just about everything related to PD. You'll find all you need to know.

[Esperanto]

It's understandable to be concerned about your wife's experiences with levodopa. While it is regarded as the "gold standard" in the early stages of PD, this sentiment may be overshadowed by various HU discussions. Open communication with her neurologist is crucial; if there are side effects or issues, it’s important to address them so that adjustments can be made accordingly.

As a partner, you can play a vital role by creating a supportive environment, collaborating on healthy lifestyle choices, and being attentive to your wife's emotional needs.

The fear of addiction to levodopa is unfounded. However, it is wise—especially for women—to aim for a minimal dosage. Research has shown that women can often manage with half the usual dose of carbidopa/levodopa, which is why they tend to experience side effects more frequently.

Moreover, delaying the initiation of medication is unnecessary, as demonstrated in research. The LEAP randomized trial found no differences in outcomes five years later between those who started levodopa immediately versus those who delayed treatment for 40 weeks.

By staying informed and engaged, you can help navigate this journey together, ensuring that your wife receives the most effective care while addressing her concerns.

[DiyChas in reply to Esperanto]

Thank you for your well thought out and easily understood reply.She has a scheduled session in a couple of months with her neurologist. We'll ask if a reduction is appropriate in her case.

[00Mark in reply to DiyChas]

It may also help to vary the times when your wife takes her meds, try a slow-release dose at bedtime, etc. Every PD patient is an individual!Best wishes to you both.

[TheGimba]

Hi,

Melatonin for sleep, Restoralax for constipation, nicotine gum for anxiety/mood. Any kind of exercise will also help. A strict sleep/wake schedule also helpful. Check with doc.