Experince with PS128?

[PHILCAM]

Hello

Is there anyone out there that has experience using L plantarum PS128?

The good bacteria

There is some research out there about being beneficial

Thoughts about use?

[JCRO]

Tried it for 6 months. Noticed no benefit, given the cost, stopped. n = 1 tho.

[PHILCAM in reply to JCRO]

Thanks for your experience although just n = 1

We are going to give it a try for 3 months and yes it is expensive

We are using Neuralli MD - 2 caps/day

We are thinking of adding B1 as well

Phil

[park_bear in reply to PHILCAM]

PS 128 did not do anything for me either, although I think some people found it helpful. Vitamin B1 has been helpful and I continue to take it.

[Estaheal]

I tried Neuralli PS 128 for six months or so. Though I did notice some overall improvement in my symptoms, I stopped taking it. This was because of 1). additives in it which are not beneficial to the gut and 2). advice from my natural health person that it won't ever establish itself.

[Boscoejean in reply to Estaheal]

I once asked a practitioner why a person has to continue taking any therapeutic probiotics and she did not seem to know the answer but said that they had to be taken daily. So I am curious which probiotics can stay in the system without being taken daily?

[00Mark]

I have never been able to discover why the PS128 strain is considered better than other strains of Lactobacillus plantarum which are cheap and easily available. I finally asked ChatGPT - see below. Meanwhile I have been taking cheaper L. plantarum tablets for about six months now. I feel slightly better in myself and my tremor is a little better, but hard to know whether that's due to the probiotic or the various other supplements I am trying.

Anyway, hope it helps you Philcam.

___________________

ChatGPT on PS128:

Lactobacillus plantarum PS128 is a specific strain of the probiotic species Lactobacillus plantarum that has been studied for its potential neuroprotective and psychotropic effects, particularly in relation to neurological conditions like Parkinson's disease (PD). Here’s what distinguishes PS128 from other, more commonly available strains:

1. Strain-Specific Benefits for Neurological and Psychological Health

Modulation of Neurotransmitters: PS128 has been shown to regulate neurotransmitter levels, especially dopamine and serotonin, which are critical in Parkinson’s disease and mood regulation. Other L. plantarum strains might not exhibit this level of specificity in affecting the gut-brain axis.

Reduction of Neuroinflammation: Studies suggest PS128 helps reduce neuroinflammation, which is a key factor in neurodegenerative diseases like PD.

Behavioral Improvements: Research on animal models has indicated that PS128 can alleviate motor deficits and anxiety-related behaviors, which are symptoms commonly experienced by individuals with Parkinson’s disease and other neurological conditions.

2. Gut-Brain Axis Mechanisms

GABA Pathway Influence: PS128 is particularly noted for its ability to interact with the GABAergic system

[Missy0202]

i have taken ps128 for years. no noticeable improvements but I feel I have also been pretty stable on so I will keep taking it

[goldiewan]

I’m taking it and think it improves mood and cognition slightly. Either way I make it from the capsules into a yoghurt which will work out much cheaper as you can keep using some of the yoghurt as a starter culture.

[mrvl in reply to goldiewan]

can you post your yoghurt recipe, thanks

[Lizzy9]

Hello ~ I’ve had my HwP on it since August of last year. HUGE help for him. Helps with his tremor/ anxiety. It took a good 2 ½ months to see benefits.

I took him off recently due to cost. Within 3 weeks tremors and anxiety were GREATLY increased. And it started calming him down again within a week after I put him back on it.

For us it’s definitely worth the cost!! And definitely worth a try. B1 didn’t help him. It did for a while but then it didn’t. Very disappointing.

Lesson learned? If everything is going well don’t change anything!!!

Have a fabulous day!

[Turnipbarrow in reply to Lizzy9]

Does he take it twice a day?

[Lizzy9 in reply to Turnipbarrow]

He takes 2 caps with breakfast and we keep them in the refrigerator.

[Lizzy9 in reply to Turnipbarrow]

Also, he takes the Bened Life PS128. Again, for us well worth the cost!!!

[Caa11]

My HWP tried it for a few weeks, more GI distress than anything- I don't know that it was enough time to see any true results. It was expensive

[Holidog]

I have been taking it for almost 2 mos and it has helped a lot with my anxiety, mood and apathy! I have not noticed any change in tremor however.

[Turnipbarrow in reply to Holidog]

Are you taking it two times a day?

[Holidog in reply to Turnipbarrow]

I take 2 capsules, once a day in the evening

[Jmellano]

took ps128 for several months, no changes good or bad

[MAJ88]

I am taking it once a day in the morning on an empty stomach for about three years already and am stable, thank god.

However, I am using the European brand/powder Neurax Biotic Spectrum by the company Neuraxpharma.

I feel the difference, when I forget to take it

Don’t want to miss it!

Good luck!