I am looking to get stem cell at Hope Bioscience in Texas. They have recommended infusion through IV and partly through Intrathecal. I am a bit nervous about getting it through intrathecal but wanted to see if anyone has had any experience with it and how effective it was and what are the associated risks.
Stem cells infusion : I am looking to get... - Cure Parkinson's
Stem cells infusion
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Prakash1
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Hi, I'm just curious about this procedure are you planning to do at Hope Biosciences. It's part of a clinical trial or it's a private treatment are you going to pay them to do? I understand the last clinical trial was recently fully recruited. Thanks.
no I am not a part of the clinical trial and am paying for the treatment
what’s the cost ? I think having the intrathecal option is actually great, see ongoing study in MSA that is purely intrathecal
It’s recommended that I get 5 sessions of infusions for 400 million cells ( 300 infused through IV and 100 intrathecal ) and is expected to cost about $8000 per session. Add to that there’s $4000 to culture and bank the cells.
Seems ok, by culture meaning it’s autologous stem cell, are they using abdominal fat cells ?
Can anyone get this treatment done? I don’t live in USA
I believe that they offer a similar treatment in Japan
To me that seems like a lot of money for a procedure with no studies to back up its effectiveness. Good luck if you decide to have it done.
Thank you
Go for it. I wish I could have the opportunity, I wouldn't think for a second
Is there any evidence that there's any efficacy to this treatment for Parkinson's?
By evidence, I mean a study published in a peer reviewed journal, not testimonials.
There's evidence for this treatment: healthunlocked.com/cure-par...
youtube.com/watch?v=s4g3kFl...
There is very strong evidence for MSA - if this is translatable to Parkinsons might be another discussion.
Are there results from the MSA study yet?
No, just the interim results from the Phase 1. The Phase 2 is currentyl ongoing and still recruiting. The phase 1 results I would consider mind-blowingly good though for MSA. The fact that they effectively had halted progression in such a fast progressing disease in pretty much all patients is just such a good result
Thanks!
I don't have personal experience of stem cell infusions but am aware of potential pros and cons. I believe it can be a game changer for some. Have you considered elevating the activity of your own stem cells? A client of mine is wearing phototherapy patches that increase stem cell activity (rather than introducing externally cultured ones). She was diagnosed with Parkinson's, but it turned out to be due to heavy metal toxicity and a genetic predisposition to poor detoxification via glutathione. She's doing really well and feels it's partly down to the patches, which are increasing stem cells and glutathione, among other things. She is also supplementing with a number of nutrients too. The cost is a factor. The patches are $100-$250 per month. Stem cell infusions are $8-10k per session.
NurturalApp, could you please share where your client has gotten the Phototherapy patches please ? I too have had heavy metal toxicity as a younger adult and diagnosed at age 50 with YOPD Parkinson's and would appreciate any info, on the phototherapy treatment modality. Thank you
Never knew that something like that existed. Where can I find the patches
I'm not convinced about them, but my daughter sells them. If you pm me, I'll give you her info.
Here is a link to the photo therapy patches lifewave.com/X39StemCellPho...
Intrathecal injection is usually a simple low risk procedure. I am sure they will give a list of the risks. I think the risk of intrathecal admin are minimal in comparison to the stem cells which are a relative unknown (Sorry if I made you swap one worry to another). My wife had to have a LP (same as intrathecal but taking fluid out instead of putting something in). The ED Dr and a radiology trainee f'd around for about 4 hours till we spat the dummy. We then got an anesthetist used to spinal injections - first go hit the spot. Later in her admission another junior Dr had a go and couldn't get the spot. Another anesthetist took over, again in first go. So get someone who has done 100 plus spinal injections.
And thanks for reporting your experience.
Hi Prakash,
Are you told what type of stem cells (i.e. UC -or AD-derived MSCs, or SVF etc) will be given?
I think it’s MSc
Good Morning,
Brilliant, go for it.
If you can just ask them the size of the stem cells they will be re-administering into you.
The smaller they are, the better chance you will have of them migrating to the brain and throughout the body to vital organs. The larger they are the more likely they will get trapped on their journey around the body and will have no benefits at all.
Best wishes and stay positive, this type of investment into getting you well is imperative, as nothing else at this stage comes close.
Good Luck
Thank you so much, they did mention that the stem cells infused through IV , only 15-20% make it through the Blood Brain Barrier and the stem cells that are infused Intrathecally 100% makes it through the BBB, which brought me to the next question as to why not just infuse all the cells via the intrathecal route. They said that it could cause the Cauda Equina syndrome which has freaked me out and which is why I posted this on this forum
Traditionally stem cells were extracted from bone marrow. But then it was found that subcutaneous fat has thousands more stem cells than equal volumes of bone marrow.
Here is a study Hope can do: C13 radiolabel stem cells and follow where they migrate after hours, days, weeks, months. Then they will know (and we will all know) where these stem cells end up. My guess is they are taken up by fast dividing cells - epithelial and skin cells, and tumors if any are around.
If I were you I would definitely want to make sure you are cancer-free before starting
I am not a doctor and this is not medical advice; make sure to discuss your plans with a doctor
I am an anesthetist and have rescued many Emergency and Surgical docs who struggled with intrathecal injections. I have done over 3000 (as these are epidural/spinal techniqes we do daily). You might want to request someone from the anesthesia department to actually inject it. All cerebral spinal fluid slowly flows north explaining how it gets to your brain. I am not aware if the IV doses cross the efficient blood brain barrier. One of you smart PhD boys can answer that one!
This is very good information and I thank you for sharing it
My guess is that if you inject the cells at L4 you will be lucky if any of them migrate past L3 in a month. I've talked to people doing research in spinal cord regeneration and they can't get these cells to go anywhere. again c13 labeled cells will tell you exactly where they end up
Good Morning Again,
I understand your concerns, so if you want to read more about Stem Cells and you have time, please read the links that I will attach below.
I have more but these are a good starting point and will give you more information that may assist you.
onlinelibrary.wiley.com/doi...
Best Wishes
when are you going to have the intrathecal administration of the stem cells and when will you have the infusions?
Over the course of two days
have you already had it or is it in the future?
I’m scheduled for next month
There is a presentation a week from today (Monday) by the International Society for Stem Cell Research called "Stem Cells and Parkinson’s Disease: Research Advances + Patient Experiences"
Cant vouch for the organization. The description and link are below.
Program Description: Co-organized by the ISSCR and the WPC, this open access webinar will provide a high-level outlook of current cell therapy research and clinical applications for Parkinson’s disease. Presenters will highlight advances in cell therapies, including basic research discoveries and the latest clinical trials. Attendees will hear a first-hand account of the journey to receive a cell therapy from a person living with Parkinson’s disease. The program is geared to people with Parkinson’s disease and their caregivers who will learn the progress toward novel cell therapy development and to researchers across the stem cell field who will gain understanding of the newest research advances and enhance their knowledge of patient perspectives. Attendees will have an opportunity to ask questions.
isscr.org/upcoming-programs...
And if you are in the US, this trial case may be important. A federal circuit court determined that Stem Cell therapy is governed by the FDA. My reading on that means higher costs, lower availability, longer delays, but less risk and higher quality products. Maybe even insurance coverage.
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