Embryonic Stem Cells

[djresd]

Has anyone had embryonic stem cells injected? We noticed Ed Begley Jr sharing his very positive experience with embryonic stems cells which were administered at Stem Cell of America in Mexico.

[jeffreyn]

Potentially interesting. Do you have a link that you could share with us?

[park_bear in reply to jeffreyn]

He does many different treatments. Not clear which is having effect:

youtu.be/luOU0woCpZg?t=252(Not working as expected?)

[djresd in reply to park_bear]

There are numerous additional videos on Stem Cell of America’s web site. Here is one from an MD Dennis H. with PD. stemcellofamerica.com/patie...

Anybody with direct knowledge?

[peeverichi in reply to djresd]

Yes I went to stem cell of America in Mexico twice and had no positive results. They were very well organized and professional. The procedure was a 45 minute intravenous session with fetal stem cells.

It was expensive, and I was motivated out of desperation and very disappointed with the lack of results.

I would not recommend them.

[djresd in reply to peeverichi]

Thank you for taking the time to reply. Did they offer an explanation for the lack of effect? When was it please.

[peeverichi in reply to djresd]

I was dx in August of 2016 and went the first time in may of 2017. I went again oct of that year still hoping. I talked to the manager and he said you look fine, you’re face is not frozen, just be patient sometimes it takes time to work.

The first time I went I took my wife who was struggling with arthritis. It did nothing for her either.

[peeverichi in reply to peeverichi]

I should mention I wasn’t talking LD yet.

[djresd in reply to jeffreyn]

healthunlocked.com/redirect...

[kaypeeoh]

Bone marrow makes stem cells and all other blood cells. It starts with basic embryonic cells that mature into the various cells: Leukocytes, lymphocytes, monocytes, macrophages, basophils, eosinophils, erythrocytes and platelet cells. The embryonal cells move to fat tissue. If fat is collected via liposuction and centrifuged the fatty tissue divides into three sections. The central part is all stem cells. The stem cells are collected and injected into tissue. There they transform into whatever cell type the body needs. This is a poor explanation and the process is much more complicated but it starts with bone marrow and ends with new tissue in the blood.

[djresd in reply to kaypeeoh]

Per the website and their consultant via phone briefing, they use neuronal cells that are between eight and 12 weeks maturity. They do this so that the cells don’t have to evolve in order to stimulate the response in the brain. This apparently facilitates a faster and more efficient effect.

healthunlocked.com/redirect...

[Bolt_Upright]

I was not aware they used fetal cells, but they do: stemcellofamerica.com/faqs/

[Lyricist]

I am wary. There is a trend - stem cell treatments administered just outside the reach of responsible authorities - on Caribbean islands, Mexico etc all claiming remarkable results. There are also respected research facilities backed by Government or by large pharmaceutical companies around the world seeking ways to use stem cells to replace the dopamine producing brain cells lost to Parkinsons. But not yet offering a treatment. The test question for any facility offering this use of stem cells as a ‘treatment’ may be to ask (1) whether they have managed to create viable substitute brain cells, (2) how they have solved the problem of their new brain cells crossing the blood brain barrier and reaching the part of the brain where they are needed and (3) where is the published research justifying any claims made?

[Biblelover]

I've had excellent success with stem cells. The biggest change was being able to coordinate my tremors with speaking. The tremors did spread to more limbs but there were enough benefits to make it worth the price. I did mine in Costa Rica.

[Zardoz in reply to Biblelover]

Biblelover,

How many treatments did you have? Cost? How long did improvement last?

thank you

[djresd in reply to Biblelover]

Thank you for taking the time to reply. Did they use fetal neuronal stems cells.

[amykp]

Unless the cells are injected directly into the brain (as they are in clinical trials here and in Europe) I fail to see how they can become useful dopamine producing neurons. They may produce dopamine (or other factors) temporarily, but how could they be a cure?

The blood brain barrier will keep them from going where they need to go and repopulating your own missing cells.

[bassofspades in reply to amykp]

even if they deliver them to the substantia nigra and t hey do become dopaminergic cells, why wouldnt they just die, too? As long as the cause is not addressed, the cure will be temporary at best. The diseased system might not be able to support them optimally.

[Racerk in reply to bassofspades]

I agreed, but if most of us DX at 60 yrs old, hopefully it last for 10 to 20 yrs and ok to do it again without side effects.

[amykp in reply to Racerk]

The ROOT cause might still be a problem (alpha-syn, toxin, whatever...) but the idea is that, injected properly, the baby neurons will implant in the substantia nigra and grow fast enough that, by the time the "cause" has caught up, you'll be 100 years old or something.

Or, better yet, the stem cell implant will tide you over until they (whoever they are : ) will find the cure for the cause.

But, in your blood, dopamine-producing neurons aren't going to do much of anything. Think about C/L. It doesn't work until it gets to your brain. In fact, until it gets to your brain, dopamine makes you nauseated. That's why you takeLevadopa, and carbdopa, to KEEP it from from turning into dopamine in your bloodstream.

There is a REASON all these stem cell clinics are offshore, a reason none of them have true blinded clinical trials, and a reason insurance won't pay a penny.

[Racerk]

Hopefully stem cell treatment can replace DBS in the future, as long as it doesn't have any neg side effects and won't make us worse.

[Sandmanliz]

they are injecting stem cells into the brain. See the last international Meeting, I believe in Copenhagen had presentations. The study I read, had 12 patients injected with two different levels of volume. The higher volume themselves did a little bit better than the lower. But all of them had improvements of 2 our feeling better per day. They also did not get worse. This was within one year. According to their scans, the cells were still viable and growing. Studies very encouraged and are starting phase 2 this year. A company in San Diego just received huge investments as well. When it starts to make people money, we will see things takeoff.

[Sandmanliz]

sorry, above should say two hours of feeling better for a day and some decreasing their meds