Produodopa

[allofatremor]

Does anyone know who’s classed as been suitable/unsuitable for this?

How does it work differently to other Dopamine meds?

I believe it’s very effective, is anyone on it?

Advice and help much appreciated

[CuriousMe12]

Nothing startlingly new.Simplistically it sounds like a soluable version of Sinemet but with a different way of having it, by continuously pumping it in to you. Useful for pwp experiencing frequent on/offs/diskinesia.

PRODUODOPA® (foslevodopa/foscarbidopa) is a solution of levodopa and carbidopa prodrugs for 24-hour continuous subcutaneous infusion for the treatment of advanced levodopa-responsive Parkinson's disease with severe motor fluctuations and hyperkinesia or dyskinesia

[allofatremor in reply to CuriousMe12]

Many thanks for that, information it’s greatly appreciated.

If I could get my husband to have enough on time it would be amazing to get him through the airport for some well needed and deserved 🌞

[jeffmayer]

I'm on the appointment pump how's it different

[allofatremor in reply to jeffmayer]

What is that? Is it making you more mobile, I believe the Produodopa really makes a difference with walking and dyskinesia x

[ZebraDoodle]

Anecdotal, but heard from a Parkinson’s nurse in a group setting:

A) her NHS trust is starting to prescribe Produodopa in limited circumstances.

B) it sounds like there is a high admin burden (unclear if this is inherent in the dosing decision process or if it’s because it’s a new drug.) Timespan of a year mentioned for some aspect (application to prescription?)

C) Being seen as an alternative to DBS in the near term (this seems to tally with the initial figure of helping 1000 people mentioned in the news). But if it goes well she could see it becoming more widespread.

I’m interested in this because of the wearing off /dyskinesia but I’m not sure quite how much it helps and whether the burden of a canular change every three days is a good trade off?

[allofatremor in reply to ZebraDoodle]

Thank you very informative x