Melatonin : I have just begun taking C/L... - Cure Parkinson's

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Melatonin

j4dx profile image
j4dx
13 Replies

I have just begun taking C/L (25/100 3x day) and am wondering if anyone has experience with combining it with Melatonin (3mg) at night before sleeping. Thanks.

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j4dx
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13 Replies
BlockRuys profile image
BlockRuys

That should be fine. Melatonin is relatively safe for longer periods.

michelagvolpe profile image
michelagvolpe

it is ok, you'll sleep and the day after you'll be more relaxed with less tremors.

HorseGarden profile image
HorseGarden

I have been on the same daily dose of C/L and melatonin (just before bed) for about 4-5 months, and find the combination gives me a better and calmer night’s sleep.

gomelgo profile image
gomelgo in reply to HorseGarden

dosage please?

smilingjane profile image
smilingjane

Hi all. Can you advice where you buy your melatonin and what the best dose is? Also what is CL?Thank you

Jane 😊

Badmouth profile image
Badmouth in reply to smilingjane

I'll buy my melatonin from Amazon. 3 mg. Also available at most pharmacies. I like the soluble tablets that you don't have to swallow.

jocelyng profile image
jocelyng

it’s fine. I take melatonin every night and have for years.

Husbandsupporter profile image
Husbandsupporter

Melatonin will not interact with Sinemet (Cd/LD). But in fairness to your body, give yourself about 20 minutes between taking Sinemet and taking the melatonin. The “cleaner” you can make the path of Sinemet to enter your system the better and then take other meds.

Stonemason1 profile image
Stonemason1

I take Pure Melatonin SR 3 mg just before bed. Then if I wake up and cant fall back asleep I take Thorne Melaton-3 and that usually puts me back asleep. I watched a youtube melatonin researcher on Parkinsons and she said the biggest need for melatonin is in the latter stages of a nights sleep. Interestingly, she thought of the drowsiness melatonin causes as a secondary side effect. Instead, she thought of the main effect as being overall brain health since PD people have depleted melatonin production. One more thing that really helps me get a full 8hrs sleep is taking 2 Nordic Naturals Magnesium Complex pills before bed. These solutions are much better than things like Ambien that results in unnatural sleep and addiction.

peminc profile image
peminc

Yes and no issues. I take 3 mg every night. I try to take it say an hour before bedtime but most often it is minutes before bedtime.

I should note that in addition to Melatonin I use lunesta 3 mg too. But that is my "hammer" used just before lights out.

Sleep is important. I use my Google fitbit watch to keep track of my sleep times, scores and total hours. Not sure I get much put of it anymore.

Tomkins profile image
Tomkins

hello

I have been taking 6mg melatonin before bed for the last 6 or so months (to address my thrashing,kicking,REM sleep disorder), along with co-careldopa modified release (25mg/100mg) and one (madopar) co-beneldopa 12.5/50mg.

Ideally I should take the melatonin an hour or so before bed but in reality I often take all meds at the same time.

I am keen to talk to the prescribing nurse - I do sleep very well - from 11pm til 8.30 or 9am but I do feel more groggy than I used. I think my episodes of flailing and kicking and shouting during sleep have reduced.

Overall, I think it’s been a positive effect on me.

My suggestion is that you note your symps and degree of grogginess daily before and after taking it.

I hope that helps

Murna

Stonemason1 profile image
Stonemason1

Two more things to add: When I first started taking melatonin my night REM sleep disturbances/thrashing etc got noticeably worse - but once I got used to the melatonin everything got better in a couple of weeks as I recall... Now I sleep more soundly with the melatonin than without.... Also - regarding your C/L - instead of 3 x 1 pills a day, I break that same dosage into 6 x 1/2 pills spread out during the day. I find that this evens out the impact of the pills so I feel better for more of the time. It is harder to avoid mealtimes for most people but since I only eat once per day, it is not a problem for me (intermittent fasting)

gomelgo profile image
gomelgo

I have been taking 5mg nightly, and still am not going to bed until hours later. Might be because I am dealing with a lot of stress at the moment and feeling driven to find my next home ... but on the night that I got desperate and took 2 of them (ie 10mg), I slept earlier and well. But then was groggy the next day, BUT with less tremor!

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