dead legs

[Teacher111]

my hip has trouble getting out of bed in AM and dead legs continues throughout the day. He physically has to lift his legs to get into the recumbent bike. This is very recent Any ideas?

[Xenos]

Hi Teacher ,

Something similar occurred for me a few month ago.

One day after I called the emergencies. They took me to the MRI immediately. And right they were : It was a stroke. I am now out of the clinic (rehab and medication), recovering slowly.

[chartist in reply to Xenos]

The following two links to a review and a meta analysis may be of interest regarding using Vinpocetine in stroke recovery :

ncbi.nlm.nih.gov/pmc/articl....

Here is a relevant quote from the review :

' VPN has noteworthy antioxidant, anti-inflammatory, and anti-apoptotic effects with inhibitory effect on glial and astrocyte cells during and following ischemic stroke (IS). VPN is effective as adjuvant therapy in the management of epilepsy; it reduces seizure frequency by 50% in a dose of 2 mg/kg/day. VPN improves psychomotor performances through modulation of brain monoamine pathway mainly on dopamine and serotonin, which play an integral role in attenuation of depressive symptoms. VPN recover cognitive functions and spatial memory through inhibition of hippocampal and cortical PDE1 with augmentation of cyclic adenosin monophosphate and cyclic guanosin monophosphate ratio, enhancement of cholinergic neurotransmission, and inhibition of neuronal inflammatory mediators. Therefore, VPN is an effective agent in the management of IS and plays an integral role in the prevention and attenuation of poststroke epilepsy, depression, and cognitive deficit through direct cAMP/cGMP-dependent pathway or indirectly through anti-inflammatory and antioxidant effects. '

And this meta analysis :

link.springer.com/article/1...

You might also consider Ginkgo Biloba Extract as discussed in this meta analysis :

pubmed.ncbi.nlm.nih.gov/323...

Here is a relevant quote from the meta analysis :

' We found 12 randomized controlled studies enrolling 1466 patients. Pooled results suggest that Ginkgo biloba use was associated with an improvement in neurological function among individuals with AIS with a reduction of 2.87 points on the National Institute of Health Stroke Scale score (95% CI: - 4.01 - - 1.74, p<0.001.Ginkgo biloba use was also associated with an improvement in activities of daily living and functional outcome (Mean Difference: 9.52; 4.66-14.33, p<0.001. Subgroup analysis suggest that the impact was larger when using an injectable formulation of Ginkgo biloba compared to the oral formulation. '

Art

[gomelgo in reply to chartist]

What is VPN?

[chartist in reply to gomelgo]

Vinpocetine.

Art

[PalmSprings]

Please update us if you learn anything. Thanks

[cceelen]

My legs and feet have long been heavy. It has been of gradual worsening that I have chalked up to PD symptoms…