The Strongest Neurotransmitter in the World is NOT Dopamine or Serotonin - Dr. Scott Sherr MD

[LAJ12345]

This is very interesting. Explains interaction of glutamate, GABA, B6, magnesium anxiety, depression

youtu.be/twNwe5WOOdI?si=dSI...(Not working as expected?)

[Boscoejean]

so what is this guy advocating that a person take?

[LAJ12345 in reply to Boscoejean]

I’m not sure - I think he has some products. I was more interested in the theory. It might explain my husbands reaction to madopar with b6 being depleted it isn’t available to help with the gaba pathway so probably why he becomes agitated and anxious and shaky with too much madopar.

[Boscoejean in reply to LAJ12345]

it looks like he is selling methylene blue lozenges

[LAJ12345 in reply to Boscoejean]

Ok

he mentions some products but they are brand names so not sure what they are

he does recommend metformin.

[Boscoejean in reply to LAJ12345]

I was trying to watch this with the sound off but I think the closed captions may not have been very accurate

I wish there was just a transcript so I could just read it rather than having to watch the video which is time consuming

[park_bear in reply to Boscoejean]

There is a transcript. View the video on YouTube, click on the "more" button at the bottom of the description, then scroll down to where it says "show transcript".

[Boscoejean in reply to park_bear]

Thanks. I did find that after I made the comment. I am glad they started doing that.

[LAJ12345 in reply to Boscoejean]

I find Americans speak very slowly so I usually listen to podcasts on 1.5 speed.

[park_bear]

Each neurotransmitter stimulates a receptor particular to that kind of neurotransmitter. Different neurotransmitters activate different receptors. They are not comparable. To say that GABA is "strongest" is ridiculous.

No offense intended to you, LAJ - my beef is with the creator of the video.

[MarionP in reply to park_bear]

Thanks for making that comment, that was my immediate reaction when I saw the word "strongest." Also, each neurotransmitter may have a dozen or more, and some cases more than a dozen and even more than that, different mechanisms, systems, and activities. It just is intellectually sloppy and suggest a person who is logically extremely ignorant, cannot think or discriminate, and who therefore should not be taken at face value, whenever they use the phraseology "best" "most" "top" "single most" etc., as it shows they don't even know or appreciate their own incomplete and excessively reductive uncritical automatic assumption making thinking process, which suggests they should not be trusted to be taken at face value anytime they speak. It's one of those "giveaway" tipoff words.

And before anybody takes a shot at me about "Pet peeve much?" let me preempt with "Yes of course, and you better be thankful that the person who designed the brakes on your car is a tight logical thinker as well."

[LAJ12345 in reply to MarionP]

I think it is more about trying to make it easy for their potential audience to grasp than the intelligence of the presenter. It is aimed at a non scientific audience who are into fitness and lifestyle so I think scientific terms might be beyond them.

[MarionP in reply to LAJ12345]

No the guy is selling something and that's why he does that. I was just saying that as a concept in general... but what he's doing is selling to everyday people without professional knowledge, and so he isn't interested in taking extra special care to be careful and accurate...in fact he is counting on it.

Most people understand when it's explained to them. And when he's not selling a specific product or service he has interest in, he is still selling...himself. a And when a professional engages in a cultural or simply common misapplication or malapropism or misapprehension, and he knows he's doing it, we also call that patronizing and pandering.

One thing people misunderstand about doctors, at least in the U.S., is that they are also quite consciously and intentionally business people. That's the culture here. When you graduate medical school with debt up to 1/2 million dollars and in some cases a million, have your internship ahead of you which entails working 16 to 20 hour days, followed by residency which will be similar hours, very low pay for both, have to pay off all that debt plus interest as they accrue and accrue and accrue, and still keep up with the rapid advance of new and ever more complicated knowledge, before even considering going into specialty training as well as passing boards and continuing to have to renew your certifications (I know one guy, son of our neighbor, who last year said he took his last board because within the next certification period he will retire...he's 65), mercantilism kind of gets under your skin... Especially if you also hope someday to have a house and a family and the sort in some kind of line with your social status, before you get to die. Doctoring here is neither cheap nor easy, and sometimes I think most other people can sometimes fail to appreciate it.

[PDKiwi]

See ncbi.nlm.nih.gov/pmc/articl... A correlation, but no mention of a UPDRS improvement with GABA supplementation .

[PDKiwi in reply to PDKiwi]

This is more encouraging ncbi.nlm.nih.gov/pmc/articl...

[Youngoma]

always get suspicious when they try to sell you something

[LAJ12345 in reply to Youngoma]

He doesn’t really push his products though .

[mauigirl18]

His troscriptions company is interesting. I've never heard of Buccal Troche before.

[LAJ12345 in reply to mauigirl18]

me neither. I suspect he has some “illegal in some countries” range

[mauigirl18 in reply to LAJ12345]

For sure!