Lions Mane Supplement

[mk2002wi]

How does one know if it's working to regrow neurons in the brain, and how long does it take?

[MBAnderson]

I posted a comment a little while ago, which I have since deleted because it turns out the studies cited were in mice, which I disregard.

healthline.com/nutrition/li...

This study may be more helpful.

ncbi.nlm.nih.gov/pmc/articl...

[Bolt_Upright in reply to MBAnderson]

That sounds pretty good: Aerobic Exercise Alters Brain Function and Structure in Parkinson's Disease: A Randomized Controlled Trial "Together with clinical results from the Park‐in‐Shape trial, 1 our results suggest that aerobic exercise stabilizes motor progression and enhances cognitive performance in individuals with PD by stimulating functional and structural plasticity in corticostriatal sensorimotor and cognitive control networks."

[park_bear in reply to Bolt_Upright]

journals.sagepub.com/doi/ep...

Randomized Controlled Trial of Community-Based Dancing to Modify Disease Progression in Parkinson Disease

"For the MDS-UPDRS-3, there was no significant change in the Control group from baseline to 12 months, whereas the Tango group had a reduction of 28.7% (12.8 points)."

If that kind of improvement came from a drug it would be worldwide headlines.

[MBAnderson in reply to park_bear]

Indeed.

[Bolt_Upright in reply to park_bear]

So the answer is, the Tango!

Tango

[LAJ12345 in reply to Bolt_Upright]

Takes 2 to tango…

[JayPwP in reply to LAJ12345]

If you get all tangled up, just tango on.

Al Pacino in Scent of Woman

[MBAnderson in reply to Bolt_Upright]

I can't bring myself to Tango - too dramatic.

There are some things worse than having PD and I think Tangoing might be one of them. 🙂

[park_bear in reply to MBAnderson]

Not really a practical alternative for me either. But, I've noticed more time I spend being up and about the better.

[Lionore in reply to MBAnderson]

Is it ok to laugh at myself trying to tango with a cane?

[CuriousMe12 in reply to park_bear]

Backed up here

parkinsons.org.uk/news/exer...

[MarionP in reply to park_bear]

Know the dangerous thing about Parkinson's?

Could lead to dancing.

[evenshoshan in reply to Bolt_Upright]

What exactly is aerobic exercise ?

[MBAnderson in reply to evenshoshan]

running, cycling, swimming, etc. - whatever increases cardio and respiration.

[evenshoshan in reply to MBAnderson]

Thanks

[Oneworld23]

I could tell that there was a benefit for me as I noticed that I had an easier time remembering things. I was starting to struggle with mundane things that a couple of years ago I would have had instant re-call. I seemed to notice a difference after about three weeks. Now it may just be a palcebo effect but something is working so I'm happy with that.

[Ghmac in reply to Oneworld23]

Do you take capsule or liquid? How much?

[Oneworld23 in reply to Ghmac]

I use liquid and half the dropper. I squeeze the rubber top and the glas fills to about halfway up and that's all I use though I hae read that you can take twicw that amount. I put it under my toungue and hold it there for as long as I can, that way it will pass the blood stream quicker

[Astrojupiter]

ncbi.nlm.nih.gov/pmc/articl...

This study mentioned was preliminary only but did look promising.

[park_bear in reply to Astrojupiter]

Only a single Parkinson study is cited in this review. That study involved pre-treatment with lion's mane, which is worthless as a test of Parkinson's treatment because it prevents Parkinson's toxic cascade from even beginning.

[park_bear]

I was only able to locate a single study that involved post treatment with lion's mane after introduction of the toxicant. In that study:

mdpi.com/2076-3921/9/2/137

" After the first MPTP injection, the mice received HEM..."

They fail to state how long after the first injection. Was it 5 minutes, 5 hours? I bet it was not 5 days. A proper study needs to create a Parkinson's like condition first, and then apply treatment.

[Gallowglass]

I take lions mane. Not sure it’s helping. Also doing Rock Steady boxing, stationary bike and brisk walking. Also sitting with my feet on a vibrating plate 10 min AM and PM—which is definitely helping my neuropathy and toe Curling.

[Turnipbarrow in reply to Gallowglass]

Can you post what the vibrating plate is that you use. My hwp has trouble with toe curling on his one foot. Thsnk you!

[Gallowglass in reply to Turnipbarrow]

Please note it’s not a cure but reduces the toe curl so you can sleep

[Gallowglass]

life Pro Waver mini

[Turnipbarrow in reply to Gallowglass]

Thank you. I will check it out.