The Swedish Medical Products Agency has granted approval for the trial to proceed; ethical approval has already been obtained from the Swedish Ethics Review Authority. The team, led from Lund University in Sweden, is poised to begin recruitment.
STEM-PD uses human embryonic stem cells, a type of cell that can turn into almost any type of cell in the body. The team has ‘programmed’ the cells to develop into dopamine nerve cell, which will be transplanted into the brains of patients to replace cells that are lost in Parkinson’s disease. The product has already been shown to be safe and effective at reverting motor deficits in animal models of Parkinson’s disease.
Suitable patients will be invited to participate in the trial; it is not possible to volunteer to participate.