ALA: Alpha-Lipoic Acid

[Discogs_discogs]

Has anyone here tried Alpha-Lipoid Acid (ALA) and noticed a difference, whether positive or negative?

[Smittybear7]

I have used it because I have read it was good to help make glutathione. I can't say that I noticed the difference but but I'll continue to to take it.

[TL500]

I took Alpha Lipoic Acid 300 from herbs of gold regularly at one stage and it seemed to help, like, lighter legs to lift, more mobile in fingers. But now I'm not sure as I read somewhere that it decreases vitamin B1 from our body and I'm trying HDT so I don't take it regularly.

[RoseBP in reply to TL500]

What is HDT?

[TL500 in reply to RoseBP]

High Dose Thiamine (vitamin B1) Therapy from dr Costantini

[RoseBP in reply to TL500]

Thanks...well that makes sense it's the initials of the therapy. Thanks again.

[Discogs_discogs in reply to TL500]

Wow. I did not know that Alpha lipoic acid lowers vitamin B1 levels.

[TL500 in reply to Discogs_discogs]

I think that I saw it said somewhere.

[jessicady in reply to TL500]

good to hear that it helps in that you feel lighter legs to life and more mobile fingers.

given that you noticed these "improvements," then you might want to continue ALA and just take HDT that works for your individual needs - that way you kinda address what's lacking and balance them off ...

B VitaminS are very important to people affected by PD. However, our individual needs (dosage that works for each of us) really vary

[TL500 in reply to jessicady]

Thanks for your suggestion. What do you mean by "just take HDT that works for your individual needs"? Thanks

[jessicady in reply to TL500]

@TL500 regarding HDT

i know some Integrative Medicine doctors prescribe different dose of Thiamine to different patients

sometimes, what works for you may not necessarilybe the appropriate dose for another person - depending on how severe the deficiency

[TL500 in reply to jessicady]

Thanks.

Are you seeing functional Dr? How much do they charge?

[LAJ12345]

my husband takes restore gold which has it in it. He takes other things so hard to tell if it helps or not but is currently doing well.

[RoseBP in reply to LAJ12345]

Where do you order Restore Gold from?

[LAJ12345 in reply to RoseBP]

wehaveparkinsons.com/

[RoseBP in reply to LAJ12345]

Thanks!

[TL500 in reply to RoseBP]

Have you heard about this before?Good results?

[TL500 in reply to LAJ12345]

can you tell what else he is taking apart from Restore Gold?

[LAJ12345 in reply to TL500]

hi, here is a photo of his list

Supplements and drugs

[TL500 in reply to LAJ12345]

Thanks very much. That's very thorough of you. Does he take PS128 too?

should we take Restore Gold and PS128; with food? Thanks

[LAJ12345 in reply to TL500]

no, we haven’t tried that yet but he is doing pretty well at the moment.

He takes all supplements with his food, then meds in between.

I thought I’d better write a list so if something happens to me someone can take over the ordering etc

[TL500 in reply to LAJ12345]

Thanks. Very kind of you. Looks like he takes lots of supplements?

[LAJ12345 in reply to TL500]

yes, mostly vitamins and minerals and plant extracts so I think of them as a supplement to food in case he is short of anything in his diet.

hardly any medications though as they don’t really agree with him

[TL500 in reply to LAJ12345]

He is very lucky to have you. You are very caring and thorough. Does he only take Azilect and Mucuna as meds?

[LAJ12345 in reply to TL500]

just madopar 50/12.5 x 3.5 , 0.5mg clonazapam spread over the day, 1/2 procyclidine.

[TL500 in reply to LAJ12345]

Looks like he's only on half a dose of levadopa?What is clonazapam and procyclidine for?

And Restore Gold, did he ever have digest distress from it?

What is closest time we can take between the doses of Restore Gold.Because have to take 4 times a day? Thanks

[LAJ12345 in reply to TL500]

yes just the half dose still.

clonazapam is a benzodiazepine, it is at a very low dose. It works on the gaba pathway to soothe anxiety . He can’t tolerate SSRIs or too much dopamine as his dopamine and seratonin pathways are blocked according to gene analysis which is borne out from experience too. Procyclidine was for rigidity. We don’t know if it helps but recently he ran out for a couple of days and felt much worse so it must do something.

He takes rg at breakfast, lunch, dinner and before bed. You can take 6 6 4 instead at meal times if they trouble you at bed with no food.

[TL500 in reply to LAJ12345]

Thanks. Can you take RG same time as B1 and other supplements or levadopa?

[LAJ12345 in reply to TL500]

yes, he takes his supplements with meals, and the others in between

[TL500 in reply to LAJ12345]

Thanks. you mean can take RG same time as B1 and other supplements or levadopa?

[LAJ12345 in reply to TL500]

he takes RG , Hardys and all the other supplements with his meals treating them like a food, then he takes his madopar between meals so it is away from protein.

[TL500 in reply to LAJ12345]

How far between first wake-up levadopa dose and breakfast?

Looks like the first and second Mucuna close to each other?

[LAJ12345 in reply to TL500]

first one about 7, then 11, 3. Last 1/2 about 8.

The natural dopamine cycle peaks at midnight, and is at a low point at midday. I am pretty sure he still produces some of his own in the evening and overnight as he can make it through from 3 in the afternoon to 7am if he needed to and still be able to move for a while in the morning. I think his problem is more utilising it.

[TL500 in reply to LAJ12345]

You mean he can go without madopar from 3pm to 7am next day?

[LAJ12345 in reply to TL500]

yes, although he struggles a little to get in and off the bed in the night without the last 1/2 but he can do it. Sometimes he forgets that last one. And they are just the half dose 50/12.5 ones too.

[TL500 in reply to LAJ12345]

That's very good.

[TL500 in reply to LAJ12345]

Just wondering what do you think of this: to me it seems that in the videos of RG testimonial, the patients are reading from a script or something, not talking, about their good experience. Do you think why?

[LAJ12345 in reply to TL500]

not sure. Maybe they feel more comfortable pre writing it and reading than making it up on the spot. Maybe they get free supplements to do review.

Hubby takes it as it has ingredients he was taking individually anyway except the tudca and it was easier and cheaper to buy RG than try and buy the tudca separately too as that is the expensive ingredient.

[TL500 in reply to LAJ12345]

Do you think their testimonials are real?

And RG reverse your husband's symptoms?

[LAJ12345 in reply to TL500]

I don’t know if they are real. If they are paid in free supplements they might be exaggerated. I don’t know how well they work as I don’t know how bad/well he would be without them. He did reduce dose last year and went through a bad patch and improved when they were increased again but there were many other factors too at the same time so impossible to pin down cause and effect.

[TL500 in reply to LAJ12345]

So you don't know before taking RG his symptoms were worse?

[LAJ12345 in reply to TL500]

Right at the start when he first was diagnosed he took it but he had first already taken most of the ingredients separately so the only new thing in it was the tudca. He also tried lots of other things like b1, b vitamins, fish oil, diet changes, berberine and allimed, exercise so had lots of changes at once. Also chelating agents. Also he came slowly off antidepressants meds.

He had a noticeable improvement 3 days after trading the other vitamins for Hardys daily essential nutrients otherwise no one thing had a noticeable change.

Over 6 month he improved gradually and lost weight, his face started working again, his PD odour went away.

Last year he was feeling good so he decreased the Hardys and RG to 3/4 dose and got worse. But also at the same time our teenager came home to stay again and caused havoc. He went back on full dose of Hardys and RG and felt better again but teenager had also gone flatting.

So many things change at once I can’t pin anything down except that Hardys seems to have an effect at the full dose.

[fel3k]

no, but HwP is trying Taurine…dr Blaylock’s book “Liver Cure” mentioned in his book good for PD

[AmmieM]

same as Smittybear

[LaVando]

I have taken ALA 600 mg for years because it really helps the burning, tingling, numbness (neuropathy) in my feet. Even just missing one day I can tell a difference in my feet. It’s an antioxidant I believe.

[chartist in reply to LaVando]

LaVando,

You may find this useful regarding Peripheral Neuropathy :

healthunlocked.com/cure-par...

Art

[jessicady]

we noticed improvements in hubby - like he became a little more talkative; he would initiate short talks and jokes; he appears less depressed since he started taking ALA

[LAJ12345 in reply to jessicady]

yes, with the supplements hubby takes, one of which is restore gold with ALA in it, he is joking and laughing a lot. He also takes 0.5 mg of clonazapam split over the day which is probably also helping with the anxiety reduction.

The downside is I am often the butt of the jokes, like how it was hilarious this morning to let the dog, a Labrador, 35kg, out of his cage early this morning and let him jump on me while I was sleeping, pinning my arms under the blankets while it licked my face. That was a very funny joke apparently 🤣. He laughed and laughed.

Albie

[TL500 in reply to jessicady]

You think it helps with depression too?How much is he taking?

Thanks

[TL500]

Does your husband see any motor improvement?