I have been documenting myself about the Parkinsoansniens synd for 5 years and, among the questions to which I try to find an explicit and relevant answer, that concerning the regular consumption and extending over 5 decades of Red Wine, although in a moderate way and without any professional or social impact.
Alcoholism-related Parkinsonism is rarely cited in medical publications and when it is, it is done in a hasty manner. Even the neuropsychiatrists I have dealt with, answered in an evasive way.
What I personally think is that regular chronic consumption, even moderate, is likely to disrupt the chemistry of the brain in the long term; whether it is reversible or not remains to be seen. as far as my experience is concerned, having stopped drinking alcohol for 32 months, I still remember that from time to time or at the end of the week I took wine (1/2), I felt an almost immediate disappearance of my synd Pakistani!
So the question that I ask is the following: can alcohol taken on a regular basis explain certain types of Parkinsonism and if so would they be irreversible?
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amar03
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And, I think you may be stuck with unsatisfying answers -- because of the snowflake syndrome, i.e., in some people it might while in others, not so. Same with reversibility. In some it might be while in others, not so.
The good news is perhaps not. "In summary, our meta-analysis suggests that alcohol consumption was associated with a decreased risk of PD, with a nearly U-shaped association."
A Link was posted to me by Thal concerning an experiment done in rodents; it goes in the opposite direction contrary to that of the authors concerned by the publication of which you had the kindness to transmit the Link! no more question of a U-shaped relationship between Parkinsonism and alcohol consumption; This is the case in the field of Neuropsychiatry where practically everything is a matter of hypotheses. That said, I think that there is no reason to despair of science: ''Today's Truth is Tomorrow's error. Thanks again for your link.
I don't know if you would have read it: '' The secret life of the L Dopa '' posted on the Forum; I find it terribly uplifting.
Sorry for not checking the author's name! Dr. BERNSTEIN (No Silver Bullet, March 22) maintained that contrary to what has been accepted for decades, there is no dopamine deficit in PD but rather an excess which is more toxic! What revolutionize the treatment of PD if he manages to get the money necessary to embark on his therapeutic trials.
Thank you for your Link which goes in the direction claimed by some concerning the risks incurred by the consumption of alcohol, however minimal it may be; concerning the deleterious action of alcohol, if it is possible to transpose what happens in rodents to humans, namely induced epigenetic modifications, this would be excellent news as regards the reversibility of the damage.
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