"Could gluten's toxicity extend to the nervous system, producing symptoms identical to classical Parkinson's disease? A remarkable case study adds to a growing body of research indicating that wheat's neurotoxicity is greatly underestimated."
"A remarkable case report describing the dramatic recovery of a 75-year-old Parkinson's disease patient after following a 3-month long gluten free diet reveals the need to explore whether there is an increased prevalence of silent or symptomatic celiac disease or non-celiac gluten sensitivity both in those afflicted with Parkinson's disease and the related multi-factorial neurodegenerative condition known as Parkinsonism."
"Wheat's "Invisible Thorns" Affect The Brain:" The defensive carbohydrate-binding protein in wheat known as wheat germ agglutinin (WGA), also know as "wheat lectin," has been found to cross the blood-brain-barrier and can interfere with neurological function in a number of ways. Read more: "Opening Pandora's Bread Box: The Critical Role of Wheat Lectin in Human Disease."
I agree gluten is bad, but not because GreenMed Info says so.
"A remarkable case report describing the dramatic recovery of a 75-year-old Parkinson's disease patient after following a 3-month long gluten free diet ..."
I don't believe this.
"Popular Health Guru Sayer Ji Curates the Scientific Literature with His Bachelor’s Degree in Philosophy"
originalText
In 2020, both Twitter and Instagram removed GreenMedInfo from their platform as part of their efforts to limit the spread of misinformation about COVID-19.[11][8] Pinterest had already banned Ji in 2018.
Hi Marc, I don't use GreenMedInfo as a source either. But they had a source for their blog post: Here is the article that blog is referencing: Dramatic improvement of parkinsonian symptoms after gluten-free diet introduction in a patient with silent celiac disease sci-hub.se/10.1007/s00415-0...
Personally, I think anybody with an autoimmune disease should give up gluten. I don't think it is the silver bullet, but I definitely believe giving up gluten is tossing unneeded cargo off a sinking ship.
I just happened to be researching this the other night. Terry Wahls, David Perlmutter, Amy Myers, and the Specific Carbohydrate Diet all ban gluten in their attempt to address IBS, MS, AD (but mostly inflammation).
I can tell it makes a huge difference for me, but I have a confirmed autoimmune disease (HT) so maybe I am not the rule.
Officially there is no way of making a dramatic recovery from PD.
I kind of think the best we can hope for is to slow and then stop progression, and then slowly improve from the point progression stopped.
I think, for most people, eliminating gluten is one of the requirements of stopping progression. And unfortunately, I don't think there is any way for a person to know if they are one of those people that needs to eliminate gluten or not, so (IMHO) it is best for anybody with PD (or anybody with any autoimmune disease) to totally cut out gluten.
I definitely wouldn't throw out GreenMed (I know nothing about them) just because Twitter and IG tossed them. During the pandemic they tossed a lot of legitimate doctors that have now been proven as having a valid, effect approach ot Covid 19.
GOOGLE "gluten and Parkinson's Disease" = 750,000 RESULTS
Here's just one clinical study -- or is NIH not good enough for you?
"Movement Disorders Related to Gluten Sensitivity: A Systematic Review"
"This review highlights that the phenomenology of gluten related movement disorders is broader than GA and demonstrates that gluten-free diet (GFD) is beneficial in a great percentage of such cases."
Good find. I think anybody with any autoimmune disease should go gluten free. Here is the article that blog is referencing: Dramatic improvement of parkinsonian symptoms after gluten-free diet introduction in a patient with silent celiac disease sci-hub.se/10.1007/s00415-0...
Google the topic for yourself and several legitimate studies report that Parkinson's is, indeed, an autoimmune disease. I've suspected as much for years
I can see why you feel that way. There are factors of auto/immunity that, I suppose, one could say, may be involved, but, when one studies the pathophysiology, of PD, with misfolding alpha synuclein clumps, etc. it can get complicated, as to causal factors, and, perhaps, for that reason, it is often not classified as an auto-immune disease. As an example, I have been diagnosed as having PD, as a neurodegenerative disease! I also am in the process of being diagnosed as having Ocular Myasthenia Gravis, which is classified, as an auto-immune disorder, on Google! So, what can I say! I understand where you are coming from! Thank you for your reply!
>>> ' Parkinson's disease (PD) is actually an autoimmune disease. Autoimmunity occurs when immune homeostasis is broken by several main mechanisms shown in this figure, which directly result in an increase in error recognition and self-attack and a decrease in self-tolerance to autoantigens. Regarding PD, chronic autoimmune attack is not only its pathogenesis but also always involved throughout the entire disease process. Inflammation is the first step of this attack, with the subsequent participation of various immune cells and immunoglobulins they produce, ultimately leading to the death of dopaminergic neurons. PRRs, pattern recognition receptors; CSF, cerebrospinal fluid; SNpc, substantia nigra pars compacta; IL, interleukin; TNF, tumor necrosis factor. ' <<<
My experience with IF is that an 8 hour eating window each day at the same time each day had no noticeable effect on me, but my experience with one meal a day IF, did have a positive effect on me, but caused me more weight loss than I wanted.
I started taking berberine again after reading this clinical study. Here's what I posted the other day about the positive benefits of PD and berberine-----------------------------------------------------
"Effect of Berberine Hydrochloride on the Diversity of Intestinal Flora in Parkinson’s Disease Patients"
"Abstract"
"This study aimed to investigate the effect of berberine hydrochloride on the diversity of intestinal flora in patients with Parkinson’s disease (PD). Prospectively selected 68 PD patients, admitted to our hospital from April 2021 to June 2021, were randomly assigned to an observation group and a control group (n = 34 per group). Patients in the control group were given conventional treatment in accordance wit"
"Patients in the observation group were administered berberine hydrochloride besides the treatment in the control group. After continuous treatment for 3 months, the enzyme-linked immunosorbent assay was applied to determine interleukin-8 (IL-8), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) levels."
"Berberine hydrochloride can improve the disorder of intestinal flora in PD patients and suppress the expression of inflammatory factors."
Conclusion
"In summary, berberine hydrochloride can suppress the expression of inflammatory factors in PD patients and improve the disorder of intestinal flora. Since the PD intestinal flora may promote the occurrence of misfolding of α-synuclein, the study concerning the PD intestinal flora and inflammatory cytokines may further supplement the therapeutic mechanism of berberine hydrochloride."
Interestingly those significant changes in inflammatory mediators and gut microbiome occurred using just 600mg of Berberine per day. Diabetics use more than double that dose per day. It would be interesting to see how the diabetic dose would perform in people with PD.
How sad that it took so long for anyone to do coeliac blood testing. Can't help but wonder about the folate, B12, one-carbon metabolism issues too. The full article talks a bit more about the possible involvement of the vitamin deficiencies and high homocysteine, but again, with those symptoms you would really expect full testing to have been done earlier (including MMA) and you wonder how much better he would have got/did get with treatment sufficient to cause any neurological improvement that was going to happen (B12 injections and then folate). We have no gold standard testing and no agreement on what is 'normal', and you can have within range B12 (even mid or high) and still be deficient. I don't have PD but other neuro (and long family history with B12 deficiencies and/or PA) and found that I needed plenty of B12, some methylfolate, and to be grain free (wheat gluten - gliadin, alone was not enough in my case, as it isn't for many). Made a vast difference.
The key word here, that clarifies thinking, in regards to classification, is inflammation! Many ailments can become much worse, with inflammation! For example, when my diagnosed osteoarthritis acts up, in an inflammatory state, I am injected with steroid treatment. I am not the decision maker, in how diseases are classified. Research scientists, and Doctor’s make those decisions! Personally, I consider Parkinson’s Disease, to be a name, for several varieties, of disease processes, affecting basal ganglia infiltration!
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