Glutathione Therapy and LDN

[slimweiss]

Just read the chapter in the LDN book about treatments for Parkinson's. Low dose naltrexone and glutathione therapy. Anyone have any experience with these? I've found several functional medicine places in the San Diego area and plan to call on Monday. We are not happy with the treatment my husband has been getting from his neurologist. His current neurologist moved. This is the second time!! I feel like we are experimenting on our own here. I know many of you can relate.

[Smittybear7]

2018 I took about 24 glutathione IVs. In addition I had a similar number of acupuncture treatments. I was diagnosed in 2017 with parkinsonism. Just started Sinemet in October 2021.ithink they both helped. I was also treating stress. At that time I was dragging my right foot and shuffling my feet and had tremors. It became cost prohibitive. I take it lot of supplements. NAC an is supposed to help the body make Glutathione. PT OT have helped tremendously.last year at this time I needed help with everything. That's why I went on medication and started PT And OT. I was making good progress and then developed some back issues. Ct SCAN- compression deformity and DEXA SCAN osteoporosis. Ot and PT are working on a program for me. I stopped exercising until I get the ok as to what I can and shouldn't do I've really regressed.Glutathione is a good idea to try.

[slimweiss in reply to Smittybear7]

Thank you for the info. My husband does take NAC and a bunch of others. Sheesh we're willing to try anything! I'm going to call several functional medicine doctors tomorrow to see if any have had success with Parkinsons patients. Have you looked into low dose naltrexone? It is supposed to help a great deal with pain. Our last neurologist said she couldn't prescribe it because it's off label. My niece is going to see if she can get some for us from across the border! Where there's a will there's a way!! There's also that procedure that I posted about earlier too. Doesn't hurt to ask. My husband fractured his L1 vertebrae and the doctor did a kyphoplasty procedure. Pretty cool. He's the same pain specialist who does the implant for pain relief. My husband also has some osteoporosis, stenosis, and arthritis. He had a laminectomy in 1981. Prolotherapy did wonders for several years. If this new procedure can dull any of his pain that would be great. Good luck to you. Hang in there and as Winston Churchill said - Never Never Never Never Never (etc.). GIVE UP!!!

[Boscoejean in reply to slimweiss]

sometime naturopaths will prescribe it - you could call and see

[gaga1958 in reply to slimweiss]

I go to a functional doctor who has offered to order LDN for me. I just haven’t gotten that far yet. Still getting used to other supplements first. But eventually will But seek out a functional dr

Know any procedures for bulging disk? Thxs

[slimweiss in reply to gaga1958]

The only info on a bulging disc is my own personal surgery for that at the C6/C7 neck vertebrae. They removed the disc and had my bones fuse together naturally. It worked great. My husband had a laminectomy in 1981 which was not a great surgery for him. They do amazing procedures now. Have you talked with an orthopedic surgeon about it? I will ask the pain specialist for ideas when we see him next and then let you know.

[Bonzu]

I am finding there is a limit to how many supplements you can take, I had blood tests done and unfortunately was on the low side of many vitamins. My monthly bill has lately gone up from an average of £240 to £300. ( And that is with a 20% discount). I don’t know if they are working but did have 6years 11 months of having just tremor. I was only taking mucuna. However the last 2 years I have developed all 4 signs of Parkinson.

[slimweiss in reply to Bonzu]

I understand. I don't even bother to add up the costs of vitamins. My family says that I could open up a pharmacy! 6 years is great. It's only been 3 since my man was diagnosed but we suspect that he's had it for much longer. He lost his sense of smell years ago, has lived a very stressful life since college, and had developed a poor posture along the way. Now he's very stooped, has a hard time dressing himself, shuffles when he walks, has dystonia mainly on the left side, has lost 25-30 lbs, and is pretty depressed about the whole thing. He does eat well and takes walks almost daily (although he did get lost a day ago....ugh - eventually found his way which should not have been difficult). He also does tai chi, rides a stationary bike, does small weights, stretches, and is having PT currently twice a week. Whatever it takes!!!Jesus bless you and strengthen you as you keep up the fight!!!

[ForViolet]

My husband has been taking LDN for many years. I had started it for Fibromyalgia/ME and decided to put him on it. It was so long ago that I've forgotten what improvements he felt, but I know it was positive, and so he continues with 3.25 ml a day.

[slimweiss in reply to ForViolet]

That's wonderful. I'm hopeful that we will find a doctor willing to prescribe it. My friend is on it for fibromyalgia too and swears by it. She bought me the LDN book. Good resource but a little over my head with all the scientific info! The Parkinson's chapter was easier to understand. Good luck to you both.

[Sydney75]

A functional medicine MD will generally prescribe it. Side effects can be vivid dreams, some take it in the am. If your husband ever needs to take any opiods including low dose tramadol they will not work as well. If you are going to have any surgery you may have to stop the LDN. We are also looking into this for my HWP as pain and fatigue are his worst symptoms. Most conventional MDs will not prescribe it. Surprisingly you can do an online appointment with a medical professional for longevity and get it prescribed. See example below. There are several of these links online. Just search get LDN online. Not sure if this would be a good idea for folks with PD as most of these are selling LDN for longevity etc. Not sure if this would work for nerve related back pain.

originalText

[slimweiss in reply to Sydney75]

Thank you for your reply. I did see that you could get the LDN online. We may try that. Every doctor/integrative medicine group just wants to do supplements. It wouldn't be a bad idea to get tested but it's pretty expensive and they don't do glutathione therapy which is another adjunct we'd like to try. I'm just so frustrated right now. My husband had been taking tramadol but I didn't like that he was because of it being an opioid. So far he's been managing on ibuprofen and Tylenol. both of those aren't great either. Keep pushing!

[Sydney75 in reply to slimweiss]

Hi we did the glutathione push for about 25 pushes. Each session made him bizarrely tired for over 12 hours. I thought maybe it interfered with his carbidopa levodopa, who knows. Not sure if it helped. Switched to liposomal. MD said it was reaction to detoxification. Wiped him out and he hates that feeling. $$$

[slimweiss in reply to Sydney75]

Oh no! That’s not good. I wonder if using a supplement might work. When you say you switched to liposomal was that glutathione supplements?

[Sydney75 in reply to slimweiss]

yes, Aurora lipsomal, but I would try the glutathione push for yourselves. PD is so unique with each person he may have good results. I also thought maybe time his C/L medication has to be far away from the injection push might be beneficial too. Good Luck. My husband has pain from lumbar spine issue/surgery too, we are seeing pain managment to see what is available thats not an opiod or gabapentin. Having two conditions that have pain as a symptom complicates things for him. May try ketamine, it is used for dyskensia in PD, and nerve pain in chronic regional pain syndrome, so we may give that a try. Well see, unfortunately all this is out of pocket costs. Several folks have posted nutraceuticals for PD and Laurie Mischely's PD school has tons of great information on slowing the progression of PD.

parkinson-school.com/

There was even a week long PD school at Bastyr University last summer. (chk that spelling).

[slimweiss in reply to Sydney75]

Awesome. I just replied to postings from a year ago about liposomal glutathione. I called several doctors in integrative medicine and none use glutathione. I'd rather he took a supplement than have another needle in him! I will look into Mischeley's info as I have read about her before.Did you see my post on the implant for pain? That's what my husband may do next.

[Sydney75 in reply to slimweiss]

I will look into that post, we have looked at the spinal cord stimulator because he does have signficant nerve damage in the lumbar area, his left thigh is completely numb post surgery (2 yrs). His pain is rather complicated, we have figured out that when he has all over body pain and maliase it is the PD. Stress, poor sleep, undermedication all can cause this type of pain for him. We did try deep muscle botox injections (the needle was 3 inches long and flexible) no real benefit just costly. He is blessed to have you!

[slimweiss in reply to Sydney75]

Thank you. I was thinking as I was reading your post that I would tell you the same thing. Caregivers are affected by this disease too! God bless you for hanging in there with him. For sleeping at night (which it seems my husband has been doing much better) - he has moderate sleep apnea but couldn't tolerate even the smallest of the devices using the machine. We decided that he may not have it as bad or at all if he sleeps on his side. We changed to that method and he is doing much better. We put a pillow between his legs and bolster his back with more pillows because of course he rolls over. He has been a back sleeper most of his life and snoring is the worst. I was getting little sleep but was afraid to leave him alone in case he had another fall or needed me for something. We finally decided that I NEEDED MY SLEEP!! Mama bear was becoming aggressive! lol. So we have been sleeping separate and it's awesome. He's doing fine and I'm getting much needed sleep.

He also takes 10 mg of melatonin and 1 tryptophan pill along with 2 different magnesiums and a C before bed. Also something for pain - lately it's been 1 all day naproxen. Seems to help!