Glutathione is an antioxidant that assists in ridding the brain of dangerous free radicals. People with PD have low levels of glutathi-one, specifically in the substantia nigra, the area in the brain where dopamine is lost. This can mean that their cells die faster and the disease progresses more quickly.
There has been some evidence that glutathione supplementation can help people with Parkinson’s.48 The practical problem in increasing glutathione levels is that it is not absorbed very well by the digestive system, so taking it orally may not be that effective. However, intravenous (IV) glutathione injections have been shown to have positive results in some cases.49 The downside of IV glutathione is that it can be expensive and difficult to access, and infection, bleeding, and blood clots are possible side effects. Taking glutathione via a nasal spray is something researchers are looking into as it is less invasive and has fewer side effects.
More clinical trials need to be done to determine whether glutathione supplements definitively work to reduce symptoms of PD. In the meantime, if you are interested in glutathione therapy, ask your doctor if it could be added to your regimen. Note that glutathione therapy is not suggested by movement disorders specialists but is offered by naturopaths.
Has anyone tried glutathione?
Glutathione injections, sublingual, or pill form 
Electroconvulsive Therapy Intervention for Parkinson’s Disease
Are some or any of the Alternative Therapies beneficial in relief of PD symptoms 
Light Therapy Clinical Trial
