Diagnosed with PD two years ago at the age of 48, I guess I’m one of the lucky few to be selected for Roche’s Prasinezumab trial, due to begin this fall.
Since my diagnosis, I don’t feel that my symptoms have gotten worse and I’m still able to keep the diagnosis to my inner circle (symptoms: slower “opening and closing” of my left index finger and thumb, than on the right hand and occasional slur and brain fog).
I’m very disciplined and try to work out 3x per week, go to the sauna and shower cold, while sticking to a mostly vegan, sugar- and gluten-free (as much as possible).
Furthermore, I am taking tons of supplements such as NADH, spermidine 2mg, 500mg vitamin B1 (thanks to you guys), 600mg Q10, NAC, etc. and, as of recently 1mg of metformin daily.
As the beginning of the trial is getting closer, I’m getting more worried about the trial’s potential negative effects. The active ingredient, Prasinezumab, is a monoclonal antibody and is supposed to eliminate alpha-synuclein.
My question to this amazing forum is, therefore, an open one: would you participate if you were me? Have you heard about other PD-studies with monoclonal antibodies and their results or side-effects? Any risks to watch out for? Positive reports welcome as well!
Questions over questions. Your input is highly appreciated. Thank you all!