Dopamine aldehyde .Relationship of chroni... - Cure Parkinson's
Dopamine aldehyde .Relationship of chronic stress and PD
The premise of this piece is wrong:
"Dopamine is a reward chemical that is implicated in motivation, and is required only to motivate and hence initiate movement...In effect, if there is no dopamine being released, there is no "joy" in movement. Conversely, if there is no motivation to move, there is no dopamine release needed"
The role of dopamine in the brain and the body is complex. There are 5 different dopamine receptors, D1 – D5 which serve different purposes:
link.springer.com/article/1...
" The dopaminergic system plays important roles in neuromodulation, such as motor control, motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a neurotransmitter, synthesized in both central nervous system and the periphery, that exerts its actions upon binding to G protein-coupled receptors. Dopamine receptors are widely expressed in the body and function in both the peripheral and the central nervous systems. Dopaminergic signaling pathways are crucial to the maintenance of physiological processes and an unbalanced activity may lead to dysfunctions that are related to neurodegenerative diseases."
In my personal experience, whether my dopamine levels are right or wrong does not affect my motivation to move. If my dopamine level is off, I can still be highly motivated to move but find movement of the affected leg difficult. If my dopamine level is correct, movement is delightfully normal.
There is so much else wrong with this piece I have to resist the temptation to go on. Conclusion: not a good source of information.
Whooops!🤫
Thank you, ParkBear for your accurate analysis of this piece. I have no scientific background so there were lots of things i didnt spotted. Im also very green in this path..im a little chicken so forgive me. What attracted me to publish it is the relationship between chronic stress and Pd. Having suffer from PSTD since i can remember i wouldn't be surprised this stress and Pd., at least in my case, are closely related...and if so, what can i do, if anything, to remedy this...
Chronic stress will aggravate any health problem and that certainly includes PD. It is definitely important to do whatever you can to de-stress.
You did nothing wrong by posting this, so no apology needed 
I am not disagreeing with PB, but... I am going to deep dive on this article. I think there may be something to glean from it. Thanks for sharing.
Yes, Bolt. There was something that resonated with me despite my science experience not going further than preparing bath bombs...and bubbles..😊🤣
I also think there's a connection between stress and Parkinson's. I'm struggling to find a way to deal with stress. Thanks for posting
Hi Smittybear. There are a few things in this post you may find of interest.
Sex and dopamine
Is chronic stress the major cause of Parkinson's?
Mannitol and Dopamine Levels
Ups and Downs of PD
