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Lixisenatide
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GLP1-R agonist improves Parkinson disease symptoms
"
Lixisenatide
can cross the blood-brain barrier and is known to have neuroprotective properties in https://www.ccjm.org/page/mds-2023/glp1-r-agonist-parkinson#:~:text=
Lixisenatide
%20can%20cross%20the%20blood,%2C%20University%20Hospital%20Bordeaux%2C%20France.
"
Lixisenatide
can cross the blood-brain barrier and is known to have neuroprotective properties in https://www.ccjm.org/page/mds-2023/glp1-r-agonist-parkinson#:~:text=
Lixisenatide
%20can%20cross%20the%20blood,%2C%20University%20Hospital%20Bordeaux%2C%20France.
Gcf51
in
Cure Parkinson's
15 days ago
Out today - Diabetes drug may slow progression of Parkinson’s
The results reveal that after 12 months, those given
lixisenatide
showed essentially no progression of motor problems, while those given the placebo showed worsening symptoms, dropping around three points on the 132-point assessment scale – a modest difference, yet thought to be clinically meaningful
The results reveal that after 12 months, those given
lixisenatide
showed essentially no progression of motor problems, while those given the placebo showed worsening symptoms, dropping around three points on the 132-point assessment scale – a modest difference, yet thought to be clinically meaningful
RBDNoPDYet
in
Cure Parkinson's
16 days ago
Diabetes drug may help slow progression of Parkinson’s – study
The progression of motor symptoms, like tremors and slowness of movement, was slowed in patients who took the treatment called
lixisenatide
, the research found. However, the research also found that nausea occurred in 46% of people receiving
lixisenatide
, and vomiting occurred in 13%.
The progression of motor symptoms, like tremors and slowness of movement, was slowed in patients who took the treatment called
lixisenatide
, the research found. However, the research also found that nausea occurred in 46% of people receiving
lixisenatide
, and vomiting occurred in 13%.
Sun_and_flowers
in
Cure Parkinson's
15 days ago
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Big News
Parkinson's treated and with symptoms less than 3 years. - If you enrolled, you received daily subcutaneous
lixisenatide
or a placebo. - The primary outcome was a change in the motor PD scale called the MDS UPDRS when on dopamine medication after one year.
Parkinson's treated and with symptoms less than 3 years. - If you enrolled, you received daily subcutaneous
lixisenatide
or a placebo. - The primary outcome was a change in the motor PD scale called the MDS UPDRS when on dopamine medication after one year.
Farooqji
in
Cure Parkinson's
16 days ago
Diabetes drug similar to Ozempic helped slow progression of Parkinson’s disease in small trial
[i]Sanofi pulled
lixisenatide
from the market at the beginning of 2023. The French drugmaker has said the discontinuation of the treatment was a business decision that was unrelated to its safety and efficacy.
[i]Sanofi pulled
lixisenatide
from the market at the beginning of 2023. The French drugmaker has said the discontinuation of the treatment was a business decision that was unrelated to its safety and efficacy.
Sydney75
in
Cure Parkinson's
15 days ago
Preliminary phase 2 trial results of lixisenatide presented
https://cureparkinsons.org.uk/2023/08/preliminary-phase-2-trial-results-of-
lixisenatide
/
https://cureparkinsons.org.uk/2023/08/preliminary-phase-2-trial-results-of-
lixisenatide
/
Parkinsonjisung
in
Cure Parkinson's
8 months ago
The 'Brain Energy Gap' and its possible implication on the progress of PD.
- As a side note - it is interesting to see that GLP-1 agonists such as
Lixisenatide
and Exenatide, which increase insulin and reduce blood sugar, in recent human trials are showing promising results. It would seem that the whole metabolic energy system is linked to PD.
- As a side note - it is interesting to see that GLP-1 agonists such as
Lixisenatide
and Exenatide, which increase insulin and reduce blood sugar, in recent human trials are showing promising results. It would seem that the whole metabolic energy system is linked to PD.
Mezmerric
in
Cure Parkinson's
9 days ago
ScienceofParkinsons: The road ahead: 2022
https://scienceofparkinsons.com/2022/01/20/road2022/ Top 5 #Parkinsons clinical trial results we will be looking out for in 2022: * Phase II
Lixisenatide
study results * Phase II Liraglutide study results * Phase II PT320 study results (Lots of GLP-1R data) * Phase II UDCA "UP study" results * Phase
https://scienceofparkinsons.com/2022/01/20/road2022/ Top 5 #Parkinsons clinical trial results we will be looking out for in 2022: * Phase II
Lixisenatide
study results * Phase II Liraglutide study results * Phase II PT320 study results (Lots of GLP-1R data) * Phase II UDCA "UP study" results * Phase
Hidden
in
Cure Parkinson's
2 years ago
DRUG REPURPOSING - DOES IT WORK? by Dr. Simon Stott
And we see this in the case of exenatide, where there are multiple ongoing
Phase 2 trials in Parkinson’s for drugs that are very similar to exenatide (such as liraglutide and
– both of which will be reporting results in 2022).
And we see this in the case of exenatide, where there are multiple ongoing
Phase 2 trials in Parkinson’s for drugs that are very similar to exenatide (such as liraglutide and
– both of which will be reporting results in 2022).
Hidden
in
Cure Parkinson's
2 years ago
More parkinson's trials
Not sure whether it's still on track after covid https://cureparkinsons.org.uk/2018/01/the-
lixisenatide
-trial/ https://clinicaltrials.gov/ct2/show/NCT03439943 And this one was in the USA, and was also originally due to report any day now https://cureparkinsons.org.uk/2020/07/the-liraglutide-trial/
Not sure whether it's still on track after covid https://cureparkinsons.org.uk/2018/01/the-
lixisenatide
-trial/ https://clinicaltrials.gov/ct2/show/NCT03439943 And this one was in the USA, and was also originally due to report any day now https://cureparkinsons.org.uk/2020/07/the-liraglutide-trial/
WinnieThePoo
in
Cure Parkinson's
3 years ago
Promising results for a GLP-1 receptor agonist. Exenatide group of PwP showed improved motor function in a randomised, double-blind trial.
Another GLP-1R agonist,
Lixisenatide
, may be more effective. There are various things to consider.
Another GLP-1R agonist,
Lixisenatide
, may be more effective. There are various things to consider.
ElliotGreen
in
Cure Parkinson's
5 years ago
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