Deterioration of brain cells in Parkinson’s disease is slowed by blocking the Bach1 protein, preclinical study shows 2021

[Bolt_Upright]

web.musc.edu/about/news-cen...

Blocking the Bach1 protein is the flip side of activating NRF2. It accomplishes the same goal. Lots of stuff in this article.

[Smittybear7]

Interesting article- thanks for sharing

[LeharLover62]

Interesting! Apparently there are already some drugs like this one approved by the FDA, so that might speed things up.

[Despe]

parkinsonsnewstoday.com/202...

Lots of discoveries. . .

[laglag]

Bolt (or anyone). I'm not good at reading a lot of studies, they are usually long and I get more confused the more I read. I appreciate the people who summarize things. The question is... they do thousands of studies with mice but they rarely work for humans. What's the deal? I'm sure there's a thousand answers, and opinions, for this. If anyone wants to give their remarks on this subject I would appreciate it. 🥊

[Bolt_Upright in reply to laglag]

Good question laglag. I think there are a number of reasons:

1: As park_bear points out often, most animal models of PD are not good models of PD. They do things to mice that simulate PD symptoms, but not the pathology of PD.

2: Mice are not humans. What works for one does not work for the other.