WHAT IS YOUR BEST SLEEPING AID? Zzzzzzzzz... - Cure Parkinson's

Cure Parkinson's

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OREOLU profile image

Hi, If you are a non tremor dominant pd patient having sleep issues, kindly help. I am currently having sleepless nights. My sleeping aid like Mirtazapine, clonazepam and Melatonin does not work for me anymore. I started with 15mg mirtazapine, 3mg melatonin and half 0.5mg clonazepam, which worked for roughly 7 to 8 months. I increased to 9mg melatonin, 30mg mirtazapine and half and a quarter of 0.5mg clonazepam which worked for only one month.

My main problem is falling asleep and staying asleep. The best I have ever got to sleep post pd diagnosis 5 plus years ago is 5hours unbroken sleep. I don't want to be hooked on too many antidepressants or anxiolytics for sleeping. So please help.

I was told at the ER last night by a doctor on call that, it is usually the parkinson's medication, that causes insomnia mostly. He however gave a new prescription for an antidepressant Trazodone. He also wants my MDS reduce/adjust my Rytary.

20 Replies

One of the side effects of Mirtazapine is insomnia. drugs.com/sfx/mirtazapine-s...

Same with Trazodone: drugs.com/sfx/trazodone-sid...

OREOLU profile image
OREOLU in reply to crimsonclover

Hi, I just do not understand why. If only drugs will not have side effects, it would have been really good to treat serious health issues like pd.

crimsonclover profile image
crimsonclover in reply to OREOLU

This video interview with Dr. Matthew Walker might be helpful, youtu.be/bEbtf7uS6P8

It is chaptered, but the whole thing is interesting (but long). Towards the end he talks about sleep medicines, alcohol, and marijuana and how they affect REM sleep. I learned a lot that I wish I'd known sooner!

OREOLU profile image
OREOLU in reply to crimsonclover

Thanks for this video. Very educative.

Mitrazapine helped me sleep

Yes, I know the feeling O! My neuro prescribed magnesium citrate and melatonin initially. Then, after a couple of weeks then prescribed 50mg of trazadone at bedtime. After taking trazadone for a month with minimal effect my neuro changed to mirtazapine which I think has been a more effective sleep aid. At about the same time, however, I also thought I would try a gummi at bedtime as well so it difficult to tell which is the most helpful. Although I am now getting about 5-6 hrs of sleep per night (rather than one or two) it still takes me two hours or so to get to sleep each night.

Other things that also help me is getting a sufficient amount of exercise each day. And, also trying to limit sugar intake after 6pm.

I cut out tea, coffee and chocolate...

Mannitol really helped. Pre diagnosis sleep was awful. After mannitol it improved a lot. Not like all the time but overall much better.I'm sure exercise is another factor. I wasn't exercising as much pre diagnosis.

Insight timer app. Lots of sleep meditation tracks.


L-tryptophan and magnesium

10 mg THC

marnegro profile image
marnegro in reply to koshca

10 mg or just 1 ml (full dropper) of Indica THC?

crimsonclover profile image
crimsonclover in reply to koshca

"Alcohol is one of the best chemicals that we know for suppressing REM sleep, alongside marijuana. By the way I should say that is THC specific..."

Link is timestamped:


Where are you based,I also took mitrazapine, but your body get used to them,I take three 300 mg of gabapetine at night supposed to be for restless legs, but they help me sleep,I'm in Scotland

OREOLU profile image
OREOLU in reply to Tilly56

Hi Tilly56

I am based in the USA. Thanks for your response.

Tilly56 profile image
Tilly56 in reply to OREOLU

I don't think this site is not for people from the uk

Very sorry to hear of sleep issues ... years ago, I had protracted and severe insomnia (got to a point where I had not more than 3 hours of fragmented sleep a night, could not nap during day, and got close to the point of collapse). Not diagnosed with PD, family has PD.

What thankfully helped me recover at the time:

Best friend gave me a Dream Hivox, an electric acupressure wristband. I had to keep turning it back on a number of times until it relaxed me enough. Natural way to relax nerves ... helped me get off drugs, which affected my memory ever since.


Red reishi (listed as #1 herb in Chinese pharmacopeia, excellent adaptogen ... deepens sleep, calms nervous system, such that even if I had little sleep, I could recover/function much better).


Also listened to a sleep CD ... Mike Brescia's Tranquil Sleep, or Deep Sleep for mental conditioning:


These three things combined were indispensable to me at the time in replacing drugs.

If your mind is racing, then there is the "military method of sleep" (can google it).

Nowadays, I take red reishi at times and magnesium bisglycinate when I need extra help relaxing. Wear sleep mask, and go sit or lie right by window where sunlight is brightest upon awaking. Perhaps you can also look into "sleep efficiency" and "sleep restriction." All the best.

OREOLU profile image
OREOLU in reply to kathy775

Hi I will look into these options.

Thanks to everyone that gave one advice or the other. Stay blessed.

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