I've been taking 3 grams of Zeolite Clinoptilolite a day for months now. Everything I have read indicates Zeolite should calm things down.
So today I am re-reading this paper and it seems to indicate that Zeolite might amplify the immune system. I have an autoimmune condition (Hashimoto's Thyroiditis) and would be concerned about amplifying my immune system. If this is going to drive inflammation I should stop taking it.
If anybody wants to take a look at this paper and let me know if you think Zeolite amplifies the immune response and/or drives inflammation, I would appreciate the feedback. I already e-mailed the author for an opinion:
Similarly, antiviral properties for clinoptilolite in vitro were shown on the human adenovirus 5, herpes simplex virus type 1, and the human enteroviruses coxsackievirus B5 and echovirus 7 (Grce and Pavelić, 2005). This effect may probably be attributed to a direct adhesion of the viral particles on clinoptilolite in vitro, which then inhibits viral entrance in the cells and viral replication. Even though no in vivo studies on clinoptilolite antiviral activity have been published thus far, positive immunomodulatory effects have been observed in patients treated for immunodeficiency disorders. In a study performed by Ivkovic et al. (2004), a significant increase in specific immunity cell counts, B lymphocite CD19+, T-helper cells CD4+, and activated T-lymphocytes HLA-DR+ were observed in subjects treated with tribomechanically micronized clinoptilolite. This effect was accompanied by significantly decreased natural immunity NK CD56+ cell counts. Again, standard blood count parameters of patients remained within normal referent values (Ivkovic et al., 2004).
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Zeolite Clinoptilolite is Pro-Inflammatory. That's Bad.
I am so stupid. I've been taking something that has probably been making me worse. And I have been evangelizing about it. So many report looked so good, but I was not smart enough to notice the finer details. Zeolite Clinoptilolite modulates immune responses. It up-modulates them (not what I expected).
So many places I read that Zeolite Clinoptilolite is anti-inflammatory. Can't figure out why they say that now. It is a superantigen and amps up the immune response:
sciencedirect.com/science/a... "As superantigens, zeolites are also responsible for the development of local inflammation, in which accumulated macrophages release large quantities of free oxygen radicals (Olanders et al., 2002). Besides reactive oxygen species, activated macrophages release tumor necrosis factor (TNF), which together with other cytokines and calcium compounds stimulates splenic T cells (Pavelic et al., 2002; Hu et al., 2013; Lamprecht et al., 2015)."
In 1984 Korkina et.al. showed that clinoptilolite particles cause hemolysis and macrophage toxicity (Kleiner, et al. 2001). Katic et al. (2006) showed that clinoptilolite can absorb the growth factors in cell media and inhibit the cell proliferation (Rivera, et al. 2005). These studies show that clinoptilolite, a kind of naturally occurring zeolite, has apoptotic, toxic and hemolysitic effects on living cells directly or indirectly. In addition to these investigations, it was found that silicates have the superantigen ability so that they can induce T cell apoptosis and may cause autoimmune diseases. Not only the T cells but also the alveolar epithelial and mesothelial cells can undergo apoptosis.
Both intrinsic and extrinsic pathways may be triggered by silicate particles (Aikoh, et al.1998, Hishumura, et al. 2006, Tomokuni, et al. 1997, Otsuki, et al. 1998, Otsuki, et al. 2000, Otsuki, et al. 2002, Matthew, et al. 2004). Ueki et al. (1994) and Aikoh et al. (1998) showed that silica; silicates and aluminosilicates act as nonspecific immunostimulators (like superantigens) (Aikoh, et al. 1998, Pavelic, et al. 2001). Also Allison et al. (1966) showed that pro-inflammatory macrophages were activated by fibrinogen silicate particulate. Silicates are the substances of which have Si ions in their structure. Clinoptilolite is that kind of substance but there was no any investigations carried out on zeolites or clinoptilolite for their effect on T lymphocyte apoptosis. In this study T lymphocyte apoptosis via clinoptilolite will be investigated, and then the pathways that can take role in apoptosis will be enlightened.
I'm so sorry for going down this path and especially for sharing it with others. This may explain my current issues with seborrheic dermatitis.
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