Selenium in the Therapy of Neurological D... - Cure Parkinson's

Cure Parkinson's

26,052 members27,350 posts

Selenium in the Therapy of Neurological Diseases. Where is it Going? 2016

Bolt_Upright profile image
4 Replies

Is anybody taking selenium? I started taking it (with Inositol) in an effort to lower my thyroid antibodies (I have HT), but I've been searching more and it seems to be helpful in most autoimmune diseases. Maybe.

Some people think PD is an autoimmune disease.

Here is the article: ncbi.nlm.nih.gov/pmc/articl...

CONCLUSIONS

Recent studies have identified Se as crucial for preserving brain function and preventing age-related neurodegenerative disorders. An insufficient supply of Se may have a detrimental effect on brain cells by exacerbating neuronal dysfunction and death. Undoubtedly, the remarkable progress that has been made in understanding the biological function of Se in the brain, especially in relation to the antioxidative and anti-inflammatory functions of selenenoproteins, has also opened up new, potential possibilities for treatment of neurodegenerative diseases by using Se as a potential drug (Fig. ​33). Thus, an assessment of optimal doses and forms of Se supplementation is still a matter of debate. On account of the higher toxicity of inorganic Se forms and, in consequence, their limited application in therapy, there is a need for a further search for Se donors, especially in organic form, in order to achieve an effective and safe therapeutic income.

Written by
Bolt_Upright profile image
Bolt_Upright
To view profiles and participate in discussions please or .
Read more about...
4 Replies
LAJ12345 profile image
LAJ12345

It is in hardys daily essential nutrients.

Rhyothemis profile image
Rhyothemis

Michael Lustgarten had a good video on selenium. He has low thyroid function, he does not take iodine but says he gets enough iodine from eating cheese (he likes cheese). I can't remember if he said he's on thyroid hormones or not:

youtu.be/IYx3Rx_B4Zo

Rhyothemis profile image
Rhyothemis

ran across something on Se today, don't think this is actionable info, but interesting:

" In brain, they demonstrated that the antioxidant activity of selenium

is considerably increased in castrated mice, compared to intact animals,

thus providing neuroprotection. This increase reveals an existing

competition between the testes and brain considering that selenium

distribution is prioritized to the testes over the brain (Pitts et al., 2015)."

frontiersin.org/articles/10...

Bolt_Upright profile image
Bolt_Upright

Thanks so much Rhyothemis! I guess if that is what it is going to take :)

I'm checking out your blog. Good stuff!

Not what you're looking for?

You may also like...

Vitamin B2 Deficiency Can Cause B6 Toxicity! PWP Are Commonly Deficient In B2.

Vitamin B6 recycling. Image credit...

Any updates on Nuplazid?

We’ve been dealing with hallucinations now off and on for almost 4 years. Hubby is still pretty...

Rethinking Parkinson’s Disease: could dopamine reduction therapy have clinical utility. (The article)

The replies in Michel0220's contribution regarding Jonathan Sackner Bernstein's theory on dopamine...

trying to consolidate b6 facts

my neuro wants to watch my b6 levels and I am trying to glean what I can about b6 in this website....

"Natural products targeting cellular processes common in Parkinson's disease and multiple sclerosis."Shamans & Witches giving meds. SAD.

I believe that the trend turning to natural products instead of evidence based medicine is...