Any experience with Kynmobi?

[desertbush]

Has anyone had experience with a new drug called Kynmobi? It purports to be an effective way to treat off times quickly - improvement in motor symptoms at 15 minutes and lasting through 90 minutes. It uses a film put under the tongue so the agent is absorbed through the mouth rather than a pill that takes time to go through the digestive system.

[Godiv]

Hi desert,This probably isn’t very helpful, but my doctor almost prescribed it for me. But she opted instead for an inhaler system that does the same thing. I think she said the inhaler is a little faster. Sorry I don’t know anything about the film, but it sounded really interesting and easy to me. More so than the inhaler which you have to load with two capsules apparently before you breathe it in.

[desertbush in reply to Godiv]

Thanks for your reply. We tried an inhaler, Inbrija, but my wife couldn't use it. You inhale a very fine "dust" and she felt like she was choking. That's why the use of a film would be better.

[Godiv in reply to desertbush]

Oh OK thank you. I can understand why she would feel that way. I probably will too. I hope the film works for her. It just sounds so much easier. The pharmacy company just called me tonight and they were describing the process of getting the inhaler ready. Good grief! Nothing you could do discreetly.

[Cropseyville]

I tried Kynmobi. A nurse starts you on 10 mg, under your tongue like you said. She takes your blood pressure, heart rate and monitors your nausea (had to take antinausea pills for 3 days before they titrated the dose of Kynmobi). Then you wait for 2 hours and they give you 15 mg, same protocol, up to 30 mg. I made it to 25 with absolutely no change in my freeze but had tachycardia. It was a two day, grueling procedure and I was so disappointed. It just did not work for me.

[desertbush in reply to Cropseyville]

Thank you for giving your experience. Very disappointing result. You always hope for some good news with this disease.