Can COVID 19 lead to Parkinson’s Disease?

[jimcaster]

I have often wondered if my Parkinson’s Disease may have stemmed from H1N1 or some other virus. Apparently, there was an uptick in PD cases following the flu epidemic of 1918 and now researchers suspect a link between COVID 19 and future PD cases.

abc.net.au/news/2020-09-23/...

[jimcaster]

Here's a Science of Parkinsons article regarding H1N1 leading to Parkinsons Disease.

scienceofparkinsons.com/tag....

[Rhyothemis in reply to jimcaster]

I had H1N1 in 2009. It was awful.

[jimcaster in reply to Rhyothemis]

When were you diagnosed?

[Rhyothemis in reply to jimcaster]

Sorry, I should have added that I don't have PD and have not been diagnosed with anything. I've had symptoms similar to my father who had MSA - which is not supposed to be hereditary and some experts think that that family history is exclusionary from diagnosis (though there have been familial cases reported in Germany and Japan). I've been much better on bunch of supplements including ubiquinol/MitoQ (the cases in Japan responded to CoQ10) and I don't think at this point I am diagnosable - the only things that really bother me now are insomnia and lower urinary tract symptoms (mostly pain, some urgency). Before the pandemic I wanted to try to get a doctor to order a neurofilament light chain test; from what I understand, Nfl can that can predict neurodegenerative disease years in advance, but won't tell you which one (but it can help distinguish between PD and MSA at later stages - higher in MSA).

[bepo in reply to jimcaster]

The CDC was recently sued, and the CDC admitted they had never done safety studies on vaccines compared to placebos.

[rescuema]

Nutritional deficiencies play a significant role in your ability to fight off viral infection, so yes if the issue goes uncorrected/exhausted and remain deficient, it can certainly increase the risk, especially when combined with increased inflammation and oxidative stress.

[Kia17]

I think anything that initiates α-Synuclein misfolding is the culprit. From virus to pesticides, molds, diet, genetic, and dozens of more causes if not hundreds that scientists have no clue.

This made finding a cure extremely hard plus that happens behind BBB where access is very limited.

[MBAnderson]

Wouldn't surprise me, none.

[Astra7]

Who made it and why??

[Rhyothemis]

Review article in Journal Of Parkinson's Disease:

Parkinsonism as a Third Wave of the COVID-19 Pandemic?

content.iospress.com/articl...

[WinnieThePoo]

Jim

There is a pile of stuff to hold the ceiling up tells us your PD started 10-15 years ago. Pick another trigger

[AaronS]

Your news article cited is a government run media outlet here in Australia. They could say the sky is turning a shade of purple, and people would believe it however only needing to take a walk outside and look with their own eyes to see it's not.

It's just fear mongering to keep people down. That's all!

[Hidden in reply to AaronS]

The article largely quotes experts. I also don't agree that the ABC is involved in "fear mongering". I'd suggest that is News Corp.

[AaronS in reply to Hidden]

Your spot on mate about News corp, they def have their own agenda

[SilentEchoes]

Idiopathic PD is an environmental illness and in my opinion the implication of a viral connection is a red herring, based on my personal experience with (documented) pesticide poisoning.

Do/did you spend a lot of time on golf courses? This activity has a more likely temporal relationship than the flu, which is linked to Guillain Barre and the flu vaccine.

When I see medical hubris like this I get tipped over. Since we are advancing theory of the origin of environmental illness and toxins here are some resources:

Suzanne Humphreys book Dissolving Illusions: Disease, Vaccines and the Forgotten History is a worthwhile read. She discusses the misuse (overdose) of aspirin and lung hemorrhage in the people who died in the 1918 pandemic.

History.com also stated that “With no cure for the [1918] flu, many doctors prescribed medication that they felt would alleviate symptoms, including aspirin, which had been trademarked by Bayer in 1899—a patent that expired in 1917, meaning new companies were able to produce the drug during the Spanish Flu epidemic.” However, determining the dosage proved to be difficult.

vaccineimpact.com/2018/did-...

We learn best when we learn for ourselves and I encourage everyone to fact check and perform your own due diligence.

Is history repeating itself with SARS-2/COVID-19?

SE

Personal anecdote, my children got very sick with H1N1 and fully recovered = permanent immunity.

My husband and I had the "Hong Kong" flu as children = permanent immunity - we also have cross immunity to H1N1 and did not get sick from our children.

There is some indication that we may also have cross immunity to SARS-2. Can anyone with knowledge weigh in on this?

And then I found this: "SARS-CoV-2, is part of a large family of coronaviruses." The virus responsible for the COVID-19 pandemic.

"Previous studies have reported that 20–50% of people who hadn’t been exposed to SARS-CoV-2 showed T cell responses against different parts of the SARS-CoV-2 virus. To investigate further, a research team led by Drs. Alessandro Sette and Daniela Weiskopf at the La Jolla Institute for Immunology tested blood samples collected between March 2015 and March 2018 for T-cell responses against different pieces of SARS-CoV-2."

Wait a minute - if this is a novel virus (never seen before) than how did some people have immunity between March 2015 and March 2018? Results were published on August 4, 2020 in Science.

Then I answered my own question - “We have now proven that, in some people, pre-existing T cell memory against common cold coronaviruses can cross-recognize SARS-CoV-2, down to the exact molecular structures,” Weiskopf says. “This could help explain why some people show milder symptoms of disease ." [Or none at all.]

This info came directly from NIH - nih.gov/news-events/nih-res...

And here: "There is substantial data from the influenza literature indicating that pre-existing cross-reactive T cell immunity can be beneficial. In the case of the H1N1 influenza pandemic of 2009, it was noted that an unusual ‘V’-shaped age distribution curve existed for disease severity, with older people faring better than younger adults. This correlated with the circulation of a different H1N1 strain in the human population decades earlier, which presumably generated pre-existing immunity in people old enough to have been exposed to it. This was verified by showing that pre-existing immunity against H1N1 existed in the general human population 9,10. It should be noted that if some degree of pre-existing immunity against SARS-CoV-2 exists in the general population, this could also influence epidemiological modelling, and suggests that a sliding scale model of COVID-19 susceptibility may be considered.

In conclusion, it is now established that SARS-CoV-2 pre-existing immune reactivity exists to some degree in the general population. It is hypothesized, but not yet proven, that this might be due to immunity to CCCs. This might have implications for COVID-19 disease severity, herd immunity and vaccine development, which still await to be addressed with actual data." nature.com/articles/s41577-...

SE